DNA methylation is a dynamic epigenetic modification with a prominent role in determining
mammalian cell development, lineage identity, and transcriptional regulation. Primarily …

Variants within non-coding genomic regions can greatly affect disease. In recent years,
increasing focus has been given to these variants, and how they can alter regulatory …

Increasing evidence suggests that transcriptional control and chromatin activities at large
involve regulatory RNAs, which likely enlist specific RNA-binding proteins (RBPs). Although …

Topoisomerase II (TOP2) relieves torsional stress by forming transient cleavage complex
intermediates (TOP2ccs) that contain TOP2-linked DNA breaks (DSBs). While TOP2ccs are …

Stochastic activation of clustered Protocadherin (Pcdh) α, β, and γ genes generates a cell-
surface identity code in individual neurons that functions in neural circuit assembly. Here, we …

Numerous pieces of evidence support the complex, 3D spatial organization of the genome
dictates gene expression. CTCF is essential to define topologically associated domain …

Axonal injury results in regenerative success or failure, depending on whether the axon lies
in the peripheral or the CNS, respectively. The present study addresses whether epigenetic …

Cell‐free DNA (cfDNA) is present in the circulating plasma and other body fluids and is
known to originate mainly from apoptotic cells. Here, we provide the first in vivo evidence of …

The basic leucine zipper transcription factor activating transcription factor-like (Batf)
contributes to transcriptional programming of multiple effector T cells and is required for T …

The development of the human cerebral cortex is a complex and dynamic process, in which
neural stem cell proliferation, neuronal migration, and post-migratory neuronal organization …