Ultrafine particle deposition in a realistic human airway at multiple inhalation scenarios

J Dong, Y Shang, L Tian, K Inthavong… - … journal for numerical …, 2019 - Wiley Online Library
The scarcity of regional deposition data in distal respiratory airways represents an important
challenge for current toxicology and pharmacology research. To bridge this gap, a realistic …

Numerical investigation of unsteady particle deposition in a realistic human nasal cavity during inhalation

X Gu, J Wen, M Wang, G Jian, G Zheng… - Experimental and …, 2019 - Springer
It is important to understand the patterns of two-phase flow in human nasal cavity in
exploring the nasal pathology knowledge. In this paper, a realistic human nasal cavity …

Numerical assessment of ambient inhaled micron particle deposition in a human nasal cavity

Y Shang, K Inthavong - Experimental and computational multiphase flow, 2019 - Springer
Understanding the particle exposure characteristics in human respiratory airways plays
important roles in assessing the therapeutic or toxic effects of inhaled particles. In this study …

Investigation of the impact of PM2. 5 on the ciliary motion of human nasal epithelial cells

J Jia, J Xia, R Zhang, Y Bai, S Liu, M Dan, T Li, T Yan… - Chemosphere, 2019 - Elsevier
Nasal epithelium provides a physical barrier to potentially harmful stimuli. Cilia, which is on
the apical side of the human nasal epithelial cells (HNEpCs), plays a critical role in removing …

Fundamentals in nasal drug delivery

Z Warnken, YJ Kim, HM Mansour, RO Williams… - Inhalation …, 2019 - taylorfrancis.com
Nasal drug delivery is a versatile route of drug administration allowing systemic delivery of
small and large molecules, treatment of local and systemic diseases, and noninvasive …

[图书][B] Computer Simulation and Analysis of Nanoparticle Delivery to the Olfactory Bulb for Direct Drug Migration to the Brain

SA Vachhani - 2019 - search.proquest.com
VACHHANI, SHANTANU AVINASH. Computer Simulation and Analysis of Nanoparticle Delivery
to the Olfactory Bulb for Direct Page 1 ABSTRACT VACHHANI, SHANTANU AVINASH …