CRISPR/Cas systems towards next-generation biosensing
Beyond its remarkable genome editing ability, the CRISPR/Cas9 effector has also been
utilized in biosensing applications. The recent discovery of the collateral RNA cleavage …
utilized in biosensing applications. The recent discovery of the collateral RNA cleavage …
Principles and applications of nucleic acid strand displacement reactions
Dynamic DNA nanotechnology, a subfield of DNA nanotechnology, is concerned with the
study and application of nucleic acid strand-displacement reactions. Strand-displacement …
study and application of nucleic acid strand-displacement reactions. Strand-displacement …
Origins and evolution of CRISPR-Cas systems
EV Koonin, KS Makarova - Philosophical Transactions of …, 2019 - royalsocietypublishing.org
CRISPR-Cas, the bacterial and archaeal adaptive immunity systems, encompass a complex
machinery that integrates fragments of foreign nucleic acids, mostly from mobile genetic …
machinery that integrates fragments of foreign nucleic acids, mostly from mobile genetic …
[HTML][HTML] Methodologies for improving HDR efficiency
M Liu, S Rehman, X Tang, K Gu, Q Fan, D Chen… - Frontiers in …, 2019 - frontiersin.org
Clustered regularly interspaced short palindromic repeats (CRISPR)-associated protein 9
(Cas9) is a precise genome manipulating technology that can be programmed to induce …
(Cas9) is a precise genome manipulating technology that can be programmed to induce …
Molecular mechanisms of RNA targeting by Cas13-containing type VI CRISPR–Cas systems
MR O'Connell - Journal of molecular biology, 2019 - Elsevier
Prokaryotic adaptive immune systems use Clustered Regularly Interspaced Short
Palindromic Repeats (CRISPRs) and CRISPR-associated (Cas) proteins for RNA-guided …
Palindromic Repeats (CRISPRs) and CRISPR-associated (Cas) proteins for RNA-guided …
Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
49624232&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
49624232&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
[HTML][HTML] CRISPR-Cas13d mediates robust RNA virus interference in plants
Background CRISPR-Cas systems endow bacterial and archaeal species with adaptive
immunity mechanisms to fend off invading phages and foreign genetic elements. CRISPR …
immunity mechanisms to fend off invading phages and foreign genetic elements. CRISPR …
[HTML][HTML] Plant genome engineering for targeted improvement of crop traits
To improve food security, plant biology research aims to improve crop yield and tolerance to
biotic and abiotic stress, as well as increasing the nutrient contents of food. Conventional …
biotic and abiotic stress, as well as increasing the nutrient contents of food. Conventional …
CRISPR ethics: moral considerations for applications of a powerful tool
C Brokowski, M Adli - Journal of molecular biology, 2019 - Elsevier
With the emergence of CRISPR technology, targeted editing of a wide variety of genomes is
no longer an abstract hypothetical, but occurs regularly. As application areas of CRISPR are …
no longer an abstract hypothetical, but occurs regularly. As application areas of CRISPR are …
[HTML][HTML] Mutagenesis in rice: the basis for breeding a new super plant
The high selection pressure applied in rice breeding since its domestication thousands of
years ago has caused a narrowing in its genetic variability. Obtaining new rice cultivars …
years ago has caused a narrowing in its genetic variability. Obtaining new rice cultivars …