Targeted protein degradation using a mutant E3 ubiquitin ligase

J Bradner, M Ishoey, D Buckley, J Paulk… - US Patent …, 2019 - Google Patents
2018-08-22 Assigned to DANA-FARBER CANCER INSTITUTE, INC. reassignment DANA-
FARBER CANCER INSTITUTE, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE …
被引用次数：18 相关文章 所有 4 个版本
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Bifunctional molecules for degradation of EGFR and methods of use

N Gray, J Jaebong, D De Clercq, M Eck… - US Patent …, 2019 - Google Patents
US10450310B2 - Bifunctional molecules for degradation of EGFR and methods of use -
Google Patents US10450310B2 - Bifunctional molecules for degradation of EGFR and …
被引用次数：5 相关文章 所有 4 个版本

Small molecule degraders of polybromo-1 (pbrm1)

E Fischer, N Gray, R Nowak, K DONOVAN, T Zhang… - 2019 - Google Patents
SCAOWHOPBSKDBI-XZOFXVEXSA-N CCC (CC) C (CC1) CCC1C (N [C@@ H](C (C)(C) C)
C (N (C [C@@ H](C1) O)[C@@ H] 1C (N [C@@ H](C) c (cc1) ccc1-c1c (C) nc [s] 1)= O)= O) …
被引用次数：2 相关文章

Bcl-2 proteins degraders for cancer treatment

G Zheng, D Zhou, X Zhang, S Khan, HE Yonghan… - 2019 - Google Patents
0 C [C@@](c (cc1) ccc1-c1c (C) nc [s] 1) NC ([C@](CCC1) N1C ([C@](C (C)(C) C) NC
(CCCCCC (N (C) CC [C@](CSc1ccccc1) Nc (ccc (S (NC (c (cc1) ccc1N1CCN (CC (CC …
被引用次数：1 相关文章

Small molecules for inducing selective protein degradation and uses thereof

KC Anderson, L Wu, J Qi, S Yan, P Park, D Chauhan - 2019 - Google Patents
GXJABQQUPOEUTA-RDJZCZTQSA-N Bortezomib Chemical compound C ([C@@ H](C (=
O) N [C@@ H](CC (C) C) B (O) O) NC (= O) C= 1N= CC= NC= 1) C1= CC= CC= C1 …
相关文章 所有 2 个版本