[HTML][HTML] Micronuclei and genome chaos: changing the system inheritance
CJ Ye, Z Sharpe, S Alemara, S Mackenzie, G Liu… - Genes, 2019 - mdpi.com
Micronuclei research has regained its popularity due to the realization that genome chaos, a
rapid and massive genome re-organization under stress, represents a major common …
rapid and massive genome re-organization under stress, represents a major common …
Occupational exposure to formaldehyde and early biomarkers of cancer risk, immunotoxicity and susceptibility
S Costa, C Costa, J Madureira, V Valdiglesias… - Environmental …, 2019 - Elsevier
Formaldehyde (FA) is a high-volume production chemical manufactured worldwide to which
many people are exposed to both environmentally and occupationally. FA was recently …
many people are exposed to both environmentally and occupationally. FA was recently …
[HTML][HTML] Chromosomes missegregated into micronuclei contribute to chromosomal instability by missegregating at the next division
B He, N Gnawali, AW Hinman, AJ Mattingly… - Oncotarget, 2019 - ncbi.nlm.nih.gov
Micronuclei (MNi) are extranuclear DNA-containing structures that form upon mitotic exit
from unsegregated chromosome fragments or anaphase lagging (whole) chromosomes …
from unsegregated chromosome fragments or anaphase lagging (whole) chromosomes …
Micronucleus cytome assays in human lymphocytes and buccal cells
C Bolognesi, M Fenech - Genotoxicity Assessment: Methods and …, 2019 - Springer
The micronucleus (MN) assay, applied in different surrogate tissues, is one of the best
validated cytogenetic techniques for evaluating chromosomal damage in humans. The …
validated cytogenetic techniques for evaluating chromosomal damage in humans. The …
Genetic damage in human populations at mining sites in the upper basin of the San Jorge River, Colombia
Á Cruz-Esquivel, J Marrugo-Negrete… - … Science and Pollution …, 2019 - Springer
Contamination with mining wastes affects the environmental health and public, especially
the human populations that live in these environments. The aim of this study was to evaluate …
the human populations that live in these environments. The aim of this study was to evaluate …
Mechanisms by which genotoxins cause micronuclei and other nuclear anomalies
M Fenech - 2019 - books.rsc.org
Normal eukaryotic cells contain a single nucleus. However, abnormal small nuclei known as
micronuclei (MN), additional to the main nucleus, may occur in cells that are exposed to …
micronuclei (MN), additional to the main nucleus, may occur in cells that are exposed to …
“Normal values” for the lymphocyte cytokinesis-block micronucleus cytome parameters: Repeatability and reproducibility in a healthy reference population
C Bolognesi, L Bonelli, A Compalati, V Ferla… - Science of The Total …, 2019 - Elsevier
The micronucleus test in peripheral blood lymphocytes is the most widely validated
technique to evaluate the DNA damage and chromosomal instability in human populations …
technique to evaluate the DNA damage and chromosomal instability in human populations …
Comparative study of micronucleus assays and dicentric plus ring chromosomes for dose assessment in particular cases of partial-body exposure
ME Mendes, JCG Mendonça… - … Journal of Radiation …, 2019 - Taylor & Francis
Purpose: The goal was to compare the micronucleus (MN) and dicentric plus ring
chromosomes (D+ R) assays for dose assessment in cases of partial body irradiations (PBI) …
chromosomes (D+ R) assays for dose assessment in cases of partial body irradiations (PBI) …
[HTML][HTML] Phorate triggers oxidative stress and mitochondrial dysfunction to enhance micronuclei generation and DNA damage in human lymphocytes
Herein, we studied phorate for its toxicological effects in human lymphocytes. Phorate
treatment for 3 h has induced significant increase in the lymphocytic DNA damage …
treatment for 3 h has induced significant increase in the lymphocytic DNA damage …
Micronuclei frequency in peripheral blood lymphocytes and levels of anti-p53 autoantibodies in serum of residents of Kowary city regions (Poland) with elevated …
K Walczak, J Olszewski, K Domeradzka-Gajda… - … /Genetic Toxicology and …, 2019 - Elsevier
Introduction Ninety four residents of Kowary city (Poland) have been investigated for
environmental radon exposure that ranged from 0.24 WLM to 9.6 WLM (activity …
environmental radon exposure that ranged from 0.24 WLM to 9.6 WLM (activity …