Specificity, polyspecificity and heterospecificity of antibody-antigen recognition
MHV Van Regenmortel… - … : A Review of 20 Years of …, 2019 - Springer
The concept of antibody specificity is analyzed and shown to reside in the ability of an
antibody to discriminate between two antigens. Initially antibody specificity was attributed to …
antibody to discriminate between two antigens. Initially antibody specificity was attributed to …
HIV/AIDS: immunochemistry, reductionism and vaccine design
MHV Van Regenmortel - Springer, Cham, doi, 2019 - Springer
According to UNAIDS, during the year 2016, 36.7 million people on our planet were living
with HIV, while 1.8 million people were newly infected by the virus. Since the start of the …
with HIV, while 1.8 million people were newly infected by the virus. Since the start of the …
Insertable variable fragments of antibodies and modified α1-α2 domains of NKG2D ligands, and non-natural NKG2D ligands that bind non-natural NKG2D receptors
K Landgraf, DP Steiger, T Baron, D Gebhart - US Patent 10,259,858, 2019 - Google Patents
US10259858B2 - Insertable variable fragments of antibodies and modified α1-α2 domains of
NKG2D ligands, and non-natural NKG2D ligands that bind non-natural NKG2D receptors …
NKG2D ligands, and non-natural NKG2D ligands that bind non-natural NKG2D receptors …
convertibleCAR-T cells provide a modular universal system for dose control of activity, flexible targeting, and versatile maintenance of CAR-cells
K Landgraf, SR Williams, D Steiger, D Gebhart, S Lok… - bioRxiv, 2019 - biorxiv.org
Current chimeric antigen receptor (CAR) cellular therapies, while remarkably efficacious,
have a number of limitations that impact their efficacy, safety and perseverance in the clinical …
have a number of limitations that impact their efficacy, safety and perseverance in the clinical …