It has long been known that endothelial Ca2+ signals drive angiogenesis by recruiting
multiple Ca2+-sensitive decoders in response to pro-angiogenic cues, such as vascular …

Oxidative post-translational modifications (oxPTM) of receptors, enzymes, ion channels and
transcription factors play an important role in cell signaling. oxPTMs are a key way in which …

We report a signaling pathway linking two fundamental functions of the ER, oxidative protein
folding, and intracellular calcium regulation. Cells sense ER oxidative protein folding …

Significance: Angiogenesis is the formation of new vessels that sprout from existing vessels.
This process is highly complex and requires a coordinated shift of the endothelial phenotype …

Mitochondria are critical organelles in eukaryotes that efficiently generate adenosine 5′-
triphosphate (ATP) for various biological activities, and any defect in the process of ATP …