Health systems rely on commercial prediction algorithms to identify and help patients with
complex health needs. We show that a widely used algorithm, typical of this industry-wide …

Pharmacoepidemiologic and pharmacoeconomic analysis of health care databases has
become a vital source of evidence to support health care decision making and efficient …

Background: The EMPA-REG OUTCOME trial (Empagliflozin Cardiovascular Outcome Event
Trial in Type 2 diabetes Mellitus Patients) showed that empagliflozin, a sodium-glucose …

Objective To investigate the rate of serious bacterial, viral or opportunistic infection in
patients with rheumatoid arthritis (RA) starting tocilizumab (TCZ) versus tumour necrosis …

Importance Whether interventions to improve food access can reduce health care use is
unknown. Objective To determine whether participation in a medically tailored meal …

OBJECTIVE Using real-world data (RWD) from three US claims data sets, we aim to predict
the findings of the CARdiovascular Outcome Trial of LINAgliptin Versus Glimepiride in Type …

Objectives Comorbidity in traumatic brain injury (TBI) has been recognised to alter the
clinical course of patients and influence short-term and long-term outcomes. We synthesised …

Background To the extent that outcomes are mediated through negative perceptions of
generics (the nocebo effect), observational studies comparing brand-name and generic …

Objective To evaluate the risk of venous thromboembolism (VTE) in rheumatoid arthritis (RA)
patients receiving tofacitinib versus those receiving tumor necrosis factor (TNF) inhibitors …

Objective: Cancer and its treatment are known to be important risk factors for sepsis,
contributing to an estimated 12% of US sepsis admissions in the 1990s. However, cancer …