JAK inhibitors for the treatment of autoimmune and inflammatory diseases
Y Jamilloux, T El Jammal, L Vuitton… - Autoimmunity …, 2019 - Elsevier
Cytokines play a central role in the pathophysiology of autoimmune and inflammatory
diseases. Several cytokines signal through the JAK-STAT pathway, which is now recognized …
diseases. Several cytokines signal through the JAK-STAT pathway, which is now recognized …
Myeloid cells during viral infections and inflammation
AA Stegelmeier, JP van Vloten, RC Mould, EM Klafuric… - Viruses, 2019 - mdpi.com
Myeloid cells represent a diverse range of innate leukocytes that are crucial for mounting
successful immune responses against viruses. These cells are responsible for detecting …
successful immune responses against viruses. These cells are responsible for detecting …
Altered N‐glycosylation profiles as potential biomarkers and drug targets in diabetes
N‐glycosylation is a ubiquitous protein modification, and N‐glycosylation profiles are
emerging as both biomarkers and functional effectors in various types of diabetes. Genome …
emerging as both biomarkers and functional effectors in various types of diabetes. Genome …
Immunological aspects of autoimmune thyroid disease–Complex interplay between cells and cytokines
J Luty, K Ruckemann-Dziurdzińska, JM Witkowski… - Cytokine, 2019 - Elsevier
Autoimmune thyroid disease (ATD) is a chronic autoimmune thyroiditis with a complex
pathogenesis including environmental factors, genetic background and immune system …
pathogenesis including environmental factors, genetic background and immune system …
Interleukin gene polymorphisms in chronic periodontitis: A case-control study in the Indian population
Objective The aim of the present study was to investigate the possible association between
seven Interleukin (IL) gene polymorphisms and their interaction with the chronic …
seven Interleukin (IL) gene polymorphisms and their interaction with the chronic …
Cytokines: the yin and yang of vitiligo pathogenesis
Introduction: Dysregulation of melanocyte function is associated with vitiligo, an idiopathic
autoimmune hypopigmentary skin disorder, caused by the selective destruction of …
autoimmune hypopigmentary skin disorder, caused by the selective destruction of …
Multivariate genome-wide association analysis of a cytokine network reveals variants with widespread immune, haematological, and cardiometabolic pleiotropy
Cytokines are essential regulatory components of the immune system, and their aberrant
levels have been linked to many disease states. Despite increasing evidence that cytokines …
levels have been linked to many disease states. Despite increasing evidence that cytokines …
Dendritic cells aggregate inflammation in experimental osteoarthritis through a toll-like receptor (TLR)-dependent machinery response to challenges
F Nie, F Ding, B Chen, S Huang, Q Liu, C Xu - Life sciences, 2019 - Elsevier
Abstract Aims Dendritic cells (DCs) and Toll-like receptor (TLR) participate in mediating
inflammation process. However, the functional role of TLR expressed on DCs in …
inflammation process. However, the functional role of TLR expressed on DCs in …
Alteration of serum levels of cytokines in schizophrenic patients before and after treatment with risperidone
Alteration of Serum Levels of Cytokines in Schizophrenic Patients before and after Treatment with
Risperidone Page 1 Copyright© June 2019, Iran J Allergy Asthma Immunol. All rights reserved …
Risperidone Page 1 Copyright© June 2019, Iran J Allergy Asthma Immunol. All rights reserved …
A study of the immunoregulatory function of TLR3 and TLR4 on mesenchymal stem cells in ankylosing spondylitis
Y Li, L Huang, Z Cai, W Deng, P Wang… - Stem cells and …, 2019 - liebertpub.com
The pathogenesis of ankylosing spondylitis (AS), an immune-mediated inflammatory
disease, remains largely unknown. We previously reported that the immunoregulatory …
disease, remains largely unknown. We previously reported that the immunoregulatory …