Reactive oxygen species (ROS) in macrophage activation and function in diabetes

E Rendra, V Riabov, DM Mossel, T Sevastyanova… - Immunobiology, 2019 - Elsevier
In a diabetic milieu high levels of reactive oxygen species (ROS) are induced. This
contributes to the vascular complications of diabetes. Recent studies have shown that ROS …

[HTML][HTML] Inflammation in renal diseases: new and old players

V Andrade-Oliveira, O Foresto-Neto… - Frontiers in …, 2019 - frontiersin.org
Inflammation, a process intimately linked to renal disease, can be defined as a complex
network of interactions between renal parenchymal cells and resident immune cells, such as …

[HTML][HTML] A single-nucleus RNA-sequencing pipeline to decipher the molecular anatomy and pathophysiology of human kidneys

BB Lake, S Chen, M Hoshi, N Plongthongkum… - Nature …, 2019 - nature.com
Defining cellular and molecular identities within the kidney is necessary to understand its
organization and function in health and disease. Here we demonstrate a reproducible …

Bioengineered human acellular vessels recellularize and evolve into living blood vessels after human implantation

RD Kirkton, M Santiago-Maysonet, JH Lawson… - Science translational …, 2019 - science.org
Traditional vascular grafts constructed from synthetic polymers or cadaveric human or
animal tissues support the clinical need for readily available blood vessels, but often come …

The global burden of diabetic kidney disease: time trends and gender gaps

B Thomas - Current diabetes reports, 2019 - Springer
Abstract Purpose of Review Diabetes mellitus prevalence is increasing throughout the world
as a consequence of growing rates of obesity, metabolic syndrome, and westernization of …

[HTML][HTML] Clinical epidemiology of infectious disease among patients with chronic kidney disease

J Ishigami, K Matsushita - Clinical and experimental nephrology, 2019 - Springer
Infectious disease is recognized as an important complication among patients with end-
stage renal disease, contributing to excess morbidity and health care costs. However, recent …

Risk of cardiovascular disease and mortality in young adults with end-stage renal disease: an analysis of the US renal data system

ZJ Modi, Y Lu, N Ji, A Kapke, DT Selewski… - JAMA …, 2019 - jamanetwork.com
Importance Cardiovascular disease (CVD) is a leading cause of death among patients with
end-stage renal disease (ESRD). Young adult (ages 22-29 years) have risks for ESRD …

Earliest evidence of preclinical diabetic retinopathy revealed using optical coherence tomography angiography perfused capillary density

RB Rosen, JSA Romo, BD Krawitz, S Mo… - American journal of …, 2019 - Elsevier
Purpose To compare perfused capillary density (PCD) in diabetic patients and healthy
controls using optical coherence tomography angiography (OCTA). Methods Forty controls …

[HTML][HTML] Intradialytic exercise improves physical function and reduces intradialytic hypotension and depression in hemodialysis patients

SY Rhee, JK Song, SC Hong, JW Choi… - The Korean journal of …, 2019 - ncbi.nlm.nih.gov
Methods We enrolled 22 patients from a hemodialysis center for a 6-month non-randomized
prospective trial. Combination of aerobic exercise with bicycle ergometer and anaerobic …

[HTML][HTML] The analysis of risk factors for diabetic nephropathy progression and the construction of a prognostic database for chronic kidney diseases

G Wang, J Ouyang, S Li, H Wang, B Lian, Z Liu… - Journal of Translational …, 2019 - Springer
Background Diabetic nephropathy (DN) affects about 40% of diabetes mellitus (DM) patients
and is the leading cause of chronic kidney disease (CKD) and end-stage renal disease …