Dopamine and addiction: what have we learned from 40 years of research

M Solinas, P Belujon, PO Fernagut, M Jaber… - Journal of Neural …, 2019 - Springer
Among the neurotransmitters involved in addiction, dopamine (DA) is clearly the best known.
The critical role of DA in addiction is supported by converging evidence that has been …

Inhibitory regulation of the prefrontal cortex following behavioral sensitization to amphetamine and/or methamphetamine psychostimulants: A review of GABAergic …

TA Wearne, JL Cornish - Progress in Neuro-Psychopharmacology and …, 2019 - Elsevier
Behavioral sensitization to repeated psychostimulant administration has been proposed to
reflect many of the neurochemical and behavioral changes that are characteristic of a range …

Structural brain characteristics of anabolic–androgenic steroid dependence in men

LE Hauger, LT Westlye, AM Fjell, KB Walhovd… - …, 2019 - Wiley Online Library
Aim To identify differences in brain morphology between dependent and non‐dependent
male anabolic–androgenic steroid (AAS) users. Design This study used cross‐sectional …

Teleosemantics, selection and novel contents

J Garson, D Papineau - Biology & Philosophy, 2019 - Springer
Mainstream teleosemantics is the view that mental representation should be understood in
terms of biological functions, which, in turn, should be understood in terms of selection …

Dopamine restores limbic memory loss, dendritic spine structure, and NMDAR-dependent LTD in the nucleus accumbens of alcohol-withdrawn rats

C Cannizzaro, G Talani, A Brancato… - Journal of …, 2019 - Soc Neuroscience
Alcohol abuse leads to aberrant forms of emotionally salient memory, ie, limbic memory, that
promote escalated alcohol consumption and relapse. Accordingly, activity-dependent …

Dopaminergic modulation of pain signals in the medial prefrontal cortex: challenges and perspectives

S Huang, SL Borgland, GW Zamponi - Neuroscience letters, 2019 - Elsevier
Chronic pain is a massive socieoeconomic burden and is often refractory to treatment. To
devise novel therapeutic interventions, it is important to understand in detail the processing …

[HTML][HTML] Identification of cytotoxic markers in methamphetamine treated rat C6 astroglia-like cells

RB Badisa, C Wiley, K Randell, SF Darling-Reed… - Scientific reports, 2019 - nature.com
Methamphetamine (METH) is a powerfully addictive psychostimulant that has a pronounced
effect on the central nervous system (CNS). The present study aimed to assess METH …

Rac1 modulates excitatory synaptic transmission in mouse retinal ganglion cells

LZ Li, N Yin, XY Li, Y Miao, S Cheng, F Li, GL Zhao… - Neuroscience …, 2019 - Springer
Ras-related C3 botulinum toxin substrate 1 (Rac1), a member of the Rho GTPase family
which plays important roles in dendritic spine morphology and plasticity, is a key regulator of …

Omega-3 fatty acid deficiency impairs frontostriatal recruitment following repeated amphetamine treatment in rats: A 7 Tesla in vivo phMRI study

RK McNamara, JD Schurdak, RH Asch… - Nutritional …, 2019 - Taylor & Francis
Although attention deficit hyperactivity disorder is associated with deficits in
docosahexaenoic acid (DHA), an omega-3 fatty acid implicated in dopamine and glutamate …

Corticostriatal plasticity in the nucleus accumbens core

NS Bamford, W Wang - Journal of neuroscience research, 2019 - Wiley Online Library
Small fluctuations in striatal glutamate and dopamine are required to establish goal‐directed
behaviors and motor learning, while large changes appear to underlie many …