[HTML][HTML] Identification of Off-Patent Compounds That Present Antifungal Activity Against the Emerging Fungal Pathogen Candida auris
HC De Oliveira, MC Monteiro, SA Rossi… - Frontiers in cellular …, 2019 - frontiersin.org
Candida auris is an emerging fungal pathogen of great concern among the scientific
community because it is causing an increasing number of hospital outbreaks of difficult …
community because it is causing an increasing number of hospital outbreaks of difficult …
An alternative strategy for combination therapy: Interactions between polymyxin B and non-antibiotics
RG Otto, E van Gorp, W Kloezen, J Meletiadis… - International journal of …, 2019 - Elsevier
Antimicrobial resistance is increasing and few new antibiotics are in the development
pipeline. Alternative strategies to treat infectious diseases, such as combination therapy, are …
pipeline. Alternative strategies to treat infectious diseases, such as combination therapy, are …
Repurposing salicylamide for combating multidrug-resistant Neisseria gonorrhoeae
M Alhashimi, A Mayhoub… - Antimicrobial agents and …, 2019 - Am Soc Microbiol
ABSTRACT The US Centers for Disease Control and Prevention (CDC) lists Neisseria
gonorrhoeae as one of the most urgent antibiotic-resistant threats in the United States. This …
gonorrhoeae as one of the most urgent antibiotic-resistant threats in the United States. This …
In vitro antimicrobial combination testing of and evolution of resistance to the first-in-class spiropyrimidinetrione zoliflodacin combined with six therapeutically relevant …
S Foerster, G Drusano, D Golparian… - Journal of …, 2019 - academic.oup.com
Abstract Objectives Resistance in Neisseria gonorrhoeae to all gonorrhoea therapeutic
antimicrobials has emerged. Novel therapeutic antimicrobials are imperative and the first-in …
antimicrobials has emerged. Novel therapeutic antimicrobials are imperative and the first-in …
Lemongrass and cinnamon bark: plant essential oil blend as a spatial repellent for mosquitoes in a field setting
DAH Peach, M Almond, R Gries… - Journal of Medical …, 2019 - academic.oup.com
Plant essential oils (EOs) have been considered as spatial repellents to help disrupt the
pathogen transmission cycle of mosquitoes. Our objective was to assess spatial repellency …
pathogen transmission cycle of mosquitoes. Our objective was to assess spatial repellency …
SAR studies on aromatic acylhydrazone-based inhibitors of fungal sphingolipid synthesis as next-generation antifungal agents
K Haranahalli, C Lazzarini, Y Sun… - Journal of medicinal …, 2019 - ACS Publications
Recently, the fungal sphingolipid glucosylceramide (GlcCer) synthesis has emerged as a
highly promising new target for drug discovery of next-generation antifungal agents, and we …
highly promising new target for drug discovery of next-generation antifungal agents, and we …
Development of a nebramine-cyclam conjugate as an antibacterial adjuvant to potentiate β-lactam antibiotics against multidrug-resistant P. aeruginosa
The β-lactams are the most widely used class of antibiotics due to their safety, effectiveness,
and spectrum of activity. As a result of their ubiquitous usage, there has been a steady rise in …
and spectrum of activity. As a result of their ubiquitous usage, there has been a steady rise in …
Dilipid ultrashort cationic lipopeptides as adjuvants for chloramphenicol and other conventional antibiotics against Gram-negative bacteria
R Domalaon, M Brizuela, B Eisner, B Findlay… - Amino Acids, 2019 - Springer
The necessity to develop therapeutic agents and strategies to abate the spread of antibiotic-
resistant pathogens is prominent. Antimicrobial peptides (AMPs) provide scaffolds and …
resistant pathogens is prominent. Antimicrobial peptides (AMPs) provide scaffolds and …
Polybasic peptide–levofloxacin conjugates potentiate fluoroquinolones and other classes of antibiotics against multidrug-resistant Gram-negative bacteria
To address the rising threat of multidrug-resistant (MDR) bacteria, new therapeutic strategies
must be developed. Efficacious drug combinations consisting of existing antibiotics and …
must be developed. Efficacious drug combinations consisting of existing antibiotics and …
[HTML][HTML] Characterization of Aspergillus tamarii Strains From Human Keratomycoses: Molecular Identification, Antifungal Susceptibility Patterns and Cyclopiazonic …
M Homa, P Manikandan, A Szekeres, N Kiss… - Frontiers in …, 2019 - frontiersin.org
Aspergillus tamarii appears to be an emerging aetiological agent of human keratomycoses
in South India. The investigated strains were isolated from six suspected fungal keratitis …
in South India. The investigated strains were isolated from six suspected fungal keratitis …