Background: During the past years biologic agents (also termed biologicals or biologics)
have become a crucial treatment option in immunological diseases. Numerous articles have …

Objective To evaluate current evidence on the efficacy and safety of topical and systemic
medications in patients with primary Sjögren syndrome (SjS) to inform European League …

Background Heterogeneity is a major obstacle to developing effective treatments for patients
with primary Sjögren's syndrome. We aimed to develop a robust method for stratification …

The Hippo pathway, an evolutionarily conserved protein kinase cascade, tightly regulates
cell growth and survival. Activation of yes‐associated protein (YAP), a downstream effector …

Objective To evaluate predictors of serious infection events (SIE s) during rituximab (RTX)
therapy and effects of hypogammaglobulinemia on SIE rates, and humoral response and its …

Objectives To evaluate the efficacy and safety of ianalumab (VAY736), a B cell-depleting, B
cell activating factor receptor-blocking, monoclonal antibody, in patients with active primary …

Objectives Systematic review with meta‐analysis of interventions for dry mouth symptoms
and hyposalivation of Sjögren's syndrome (SS). Materials and Methods We searched …

Primary biliary cholangitis (PBC) is a chronic cholestatic liver disease. Half of patients
experience debilitating fatigue, which is currently untreatable. Previous studies have shown …

Objective Although a role for CD 4+ T cells in the pathogenesis of Sjögren's syndrome (SS)
has been documented, the pathogenic significance of CD 8+ T cells is unclear. The aim of …

Primary Sjögren's syndrome (pSS) is an autoimmune connective tissue disease
characterised by an enhanced lymphoproliferative status, with a greater risk of hesitating in …