Bone disease is a cardinal complication of multiple myeloma that affects quality of life and
survival. Osteocytes have emerged as key players in the development of myeloma-related …

Coupling during bone remodeling refers to the spatial and temporal coordination of bone
resorption with bone formation. Studies have assessed the subtle interactions between …

Aim In this article, the interplay between bone resorbing and bone forming cells is reviewed.
Method This review examines the comprehensive literature on the interaction between bone …

Regenerative paradigms exhibit nerve dependency, including regeneration of the mouse
digit tip and salamander limb. Denervation impairs regeneration and produces …

Pathological bone loss is caused by an imbalance between bone formation and resorption.
The bone microenvironments are hypoxic, and hypoxia-inducible factor (HIF) is known to …

Previous studies have reported that octacalcium phosphate (OCP) enhances osteoblast
differentiation and osteoclast formation during the hydrolysis process to hydroxyapatite (HA) …

Fibrous dysplasia of bone/McCune‐Albright syndrome (Polyostotic FD/MAS; OMIM#
174800) is a crippling skeletal disease caused by gain‐of‐function mutations of Gsα …

Extracellular vesicles (EVs) are shed by all eukaryotic cells and have emerged as important
intercellular regulators. EVs released by osteoclasts were recently identified as important …

Bone is one of the preferred sites for the metastasis of malignant tumours, such as breast
cancer, lung cancer and malignant melanoma. Tumour cells colonizing bone have the …

Background Previously, we found that (−)-epigallocatechin-3-gallate (EGCG) enhanced
osteogenic differentiation of murine bone marrow mesenchymal stem cells by increasing the …