Interferon-γ enhances the antifibrotic effects of pirfenidone by attenuating IPF lung fibroblast activation and differentiation
TN Vu, X Chen, HD Foda, GC Smaldone… - Respiratory …, 2019 - Springer
Background Idiopathic pulmonary fibrosis (IPF) pathogenesis involves multiple pathways,
and combined antifibrotic therapy is needed for future IPF therapy. Inhaled interferon-γ (IFN …
and combined antifibrotic therapy is needed for future IPF therapy. Inhaled interferon-γ (IFN …
Efficacy of bone marrow mesenchymal stem cell transplantation in animal models of pulmonary fibrosis after exposure to bleomycin: A meta‑analysis
E Zhang, YE Yang, J Zhang… - Experimental and …, 2019 - spandidos-publications.com
Previous studies have demonstrated that bone marrow mesenchymal stem cell (BMSC)
transplantation is a promising treatment strategy for pulmonary fibrosis. Although …
transplantation is a promising treatment strategy for pulmonary fibrosis. Although …
[HTML][HTML] Combination of L-Arginine and L-Norvaline protects against pulmonary fibrosis progression induced by bleomycin in mice
L Gao, JH Zhang, XX Chen, HL Ren, XL Feng… - Biomedicine & …, 2019 - Elsevier
Pulmonary fibrosis (PF) progression may be involved with arginine (Arg) metabolism and
immune balance. The present study aimed to explore the effects of L-Arginine (L-Arg) and L …
immune balance. The present study aimed to explore the effects of L-Arginine (L-Arg) and L …
[HTML][HTML] Tackling MARCKS-PIP3 circuit attenuates fibroblast activation and fibrosis progression
Targeting activated fibroblasts, including myofibroblast differentiation, has emerged as a key
therapeutic strategy in patients with idiopathic pulmonary fibrosis (IPF). However, there is no …
therapeutic strategy in patients with idiopathic pulmonary fibrosis (IPF). However, there is no …
Transforming growth factor β1 alters the 3′-UTR of mRNA to promote lung fibrosis
J Ko, T Mills, J Huang, N Chen, TCJ Mertens… - Journal of Biological …, 2019 - ASBMB
Idiopathic pulmonary fibrosis (IPF) is a chronic disease characterized by the pathological
remodeling of air sacs as a result of excessive accumulation of extracellular matrix (ECM) …
remodeling of air sacs as a result of excessive accumulation of extracellular matrix (ECM) …
YKL-40 is a local marker for inflammation in patients with pseudoexfoliation syndrome
T Gonen, S Guzel, KH Keskinbora - Eye, 2019 - nature.com
Purpose To investigate the YKL-40, as a marker of inflammation, in aqueous humor and
serum of cataract patients with and without pseudoexfoliation syndrome (PEX). Methods …
serum of cataract patients with and without pseudoexfoliation syndrome (PEX). Methods …
Ameliorative potential of biguanides on experimentally-induced lung fibrosis
M Abd Elmaaboud, M Balaha… - Bulletin of Egyptian …, 2019 - journals.ekb.eg
Lung fibrosis is a disease that carries poor prognosis and high mortality rate. The
mechanisms of fibrosis may include disordered wound healing, infiltration with inflammatory …
mechanisms of fibrosis may include disordered wound healing, infiltration with inflammatory …
Inhibition of the Stem cell factor 248 isoform attenuates the development of pulmonary remodeling disease 2
W Lukacs - journals.physiology.org
22 Stem cell factor (SCF) and its receptor c-kit have been implicated in inflammation, tissue
23 remodeling, and fibrosis. Ingenuity® Integrated Pathway Analysis (IPA) of gene …
23 remodeling, and fibrosis. Ingenuity® Integrated Pathway Analysis (IPA) of gene …
Comorbid Metabolic Disorders in Chronic Lung Diseases
MI Gumeniuk - Infusion & Chemotherapy, 2019 - infusion-chemotherapy.com
BACKGROUND. Chronic obstructive pulmonary disease (COPD), asthma and interstitial
lung diseases (ILD) are often accompanied by various metabolic disorders, aggravating the …
lung diseases (ILD) are often accompanied by various metabolic disorders, aggravating the …