MicroRNAs and complex diseases: from experimental results to computational models
Plenty of microRNAs (miRNAs) were discovered at a rapid pace in plants, green algae,
viruses and animals. As one of the most important components in the cell, miRNAs play a …
viruses and animals. As one of the most important components in the cell, miRNAs play a …
HMDD v3. 0: a database for experimentally supported human microRNA–disease associations
Comprehensive databases of microRNA–disease associations are continuously demanded
in biomedical researches. The recently launched version 3.0 of Human MicroRNA Disease …
in biomedical researches. The recently launched version 3.0 of Human MicroRNA Disease …
miARma-Seq, a comprehensive pipeline for the simultaneous study and integration of miRNA and mRNA expression data
E Andrés-León, AM Rojas - Methods, 2019 - Elsevier
Messenger RNAs (mRNAs) fulfil specific biological roles in cells and, thus, their expression
may be adapted to suit specific circumstances. This is in part achieved through selective …
may be adapted to suit specific circumstances. This is in part achieved through selective …
Multi-view manifold regularized learning-based method for prioritizing candidate disease miRNAs
MicroRNAs (miRNAs) are emerging as key regulators and have been reported to play
critical roles in diverse cellular processes. Previous findings have shown that aberrant …
critical roles in diverse cellular processes. Previous findings have shown that aberrant …
maTE: discovering expressed interactions between microRNAs and their targets
Motivation Disease is often manifested via changes in transcript and protein abundance.
MicroRNAs (miRNAs) are instrumental in regulating protein abundance and may …
MicroRNAs (miRNAs) are instrumental in regulating protein abundance and may …
[HTML][HTML] Elevated plasma microRNA-105-5p level in patients with idiopathic Parkinson's disease: a potential disease biomarker
Z Yang, T Li, Y Cui, S Li, C Cheng, B Shen… - Frontiers in …, 2019 - frontiersin.org
Parkinson's disease (PD) is the second most common neurodegenerative disease, which
still lacks a biomarker to aid in diagnosis and to differentiate diagnosis at the early stage of …
still lacks a biomarker to aid in diagnosis and to differentiate diagnosis at the early stage of …
[HTML][HTML] Transcriptome analysis of miRNA and mRNA in the livers of pigs with highly diverged backfat thickness
K Xing, X Zhao, H Ao, S Chen, T Yang, Z Tan… - Scientific reports, 2019 - nature.com
Fat deposition is very important in pig production, and its mechanism is not clearly
understood. MicroRNAs (miRNAs) play critical roles in fat deposition and energy …
understood. MicroRNAs (miRNAs) play critical roles in fat deposition and energy …
Computational resources for prediction and analysis of functional miRNA and their targetome
Abstract microRNAs are evolutionarily conserved, endogenously produced, noncoding
RNAs (ncRNAs) of approximately 19–24 nucleotides (nts) in length known to exhibit gene …
RNAs (ncRNAs) of approximately 19–24 nucleotides (nts) in length known to exhibit gene …
Analysis of the role of mutations in the KMT 2D histone lysine methyltransferase in bladder cancer
B Ding, L Yan, Y Zhang, Z Wang, Y Zhang… - FEBS open …, 2019 - Wiley Online Library
Histone lysine methyltransferases (HMT) comprise a subclass of epigenetic regulators;
dysregulation of these enzymes affects gene expression, which may lead to tumorigenesis …
dysregulation of these enzymes affects gene expression, which may lead to tumorigenesis …
Computational prediction of functional microRNA–mRNA interactions
Proteins have a strong influence on the phenotype and their aberrant expression leads to
diseases. MicroRNAs (miRNAs) are short RNA sequences which posttranscriptionally …
diseases. MicroRNAs (miRNAs) are short RNA sequences which posttranscriptionally …