Long-term disability progression of pediatric-onset multiple sclerosis

KA McKay, J Hillert, A Manouchehrinia - Neurology, 2019 - AAN Enterprises
Objective To evaluate long-term disability progression in pediatric-onset multiple sclerosis
(POMS) and compare to adult-onset multiple sclerosis (AOMS). Methods This was a …

Multiple sclerosis risk factors contribute to onset heterogeneity

FBS Briggs, CY Justin, MF Davis, J Jiangyang… - Multiple sclerosis and …, 2019 - Elsevier
Background The phenotypic presentation of multiple sclerosis (MS) may predict long-term
outcomes and little is known about factors contributing to heterogeneity at MS onset. Given …

[HTML][HTML] Familial risk of early-and late-onset multiple sclerosis: a Swedish nationwide study

J Song, H Westerlind, KA McKay, C Almqvist… - Journal of …, 2019 - Springer
Background Persons who develop multiple sclerosis (MS) at a young age may bear a higher
genetic risk load than persons who develop MS later in life; however, the contribution of …

Is multiple sclerosis progression associated with the HLA-DR15 haplotype?

KH Stürner, I Siembab, G Schön… - Multiple sclerosis …, 2019 - journals.sagepub.com
Background The prevalence of multiple sclerosis is associated with the major
histocompatibility complex class II DR15 haplotype HLA-DRB1* 15: 01∼ HLA-DRB5* 01 …

Deconstruction of HLA-DRB1*04:01:01 and HLA-DRB1*15:01:01 class II haplotypes using next-generation sequencing in European-Americans with multiple …

LE Creary, KC Mallempati… - Multiple Sclerosis …, 2019 - journals.sagepub.com
Background: The association between HLA-DRB1* 15: 01 with multiple sclerosis (MS)
susceptibility is well established, but the contribution of the tightly associated HLA-DRB5 …

Regulation of oligodendrocyte differentiation: new targets for drug discovery in remyelination

F de Castro, F Josa-Prado - 2019 - books.rsc.org
The only myelin-forming cells in the central nervous system (CNS) are oligodendrocytes,
originally identified as 'glia with very few processes' by brilliant Spanish neuroscientist Pío …

[PDF][PDF] Association of MMP9 polymorphism rs3918242 with clinical findings in Slovak multiple sclerosis patients

V Durmanova, Z Parnicka, J Javor… - Act Nerv Super …, 2019 - rediviva.sav.sk
OBJECTIVES: Multiple sclerosis (MS) is a chronic inflammatory neurodegenerative disease
affecting mostly young people. Matrix metalloproteinases (MMPs) are zinc-dependent …

[PDF][PDF] Regulation of MHC II Protein Expression by Lysosomal Degradation and Vitamin D.

N Shah - 2019 - pure.roehampton.ac.uk
Major histocompatibility complex class II (MHC II) proteins display peptides to CD4+ T cells.
Their regulation of expression is important for normal immune function and autoimmunity …

[图书][B] B cell: Glial cell interactions and contribution to CNS-compartmentalized inflammation in Multiple Sclerosis

H Touil - 2019 - search.proquest.com
Growing evidence suggests that B cells play important roles during disease relapses and
possibly also during the progressive stages of multiple sclerosis (MS). A number of studies …

[引用][C] Multiple skleroz hastalarında WNT sinyal yolağında görev alan miRNA ekspresyon seviyelerinin belirlenmesi

E Yaşar - platform.almanhal.com
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