[HTML][HTML] A brief history of protein sorting prediction

H Nielsen, KD Tsirigos, S Brunak, G von Heijne - The protein journal, 2019 - Springer
Ever since the signal hypothesis was proposed in 1971, the exact nature of signal peptides
has been a focus point of research. The prediction of signal peptides and protein subcellular …

[HTML][HTML] Comparison of open-source reverse vaccinology programs for bacterial vaccine antigen discovery

M Dalsass, A Brozzi, D Medini, R Rappuoli - Frontiers in immunology, 2019 - frontiersin.org
Reverse Vaccinology (RV) is a widely used approach to identify potential vaccine
candidates (PVCs) by screening the proteome of a pathogen through computational …

Advances in predicting subcellular localization of multi-label proteins and its implication for developing multi-target drugs

KC Chou - Current medicinal chemistry, 2019 - ingentaconnect.com
The smallest unit of life is a cell, which contains numerous protein molecules. Most of the
functions critical to the cell's survival are performed by these proteins located in its different …

[HTML][HTML] Immunoinformatics-Aided Design and Evaluation of a Potential Multi-Epitope Vaccine against Klebsiella Pneumoniae

HA Dar, T Zaheer, M Shehroz, N Ullah, K Naz… - Vaccines, 2019 - mdpi.com
Klebsiella pneumoniae is an opportunistic gram-negative bacterium that causes nosocomial
infection in healthcare settings. Despite the high morbidity and mortality rate associated with …

pLoc_bal-mAnimal: predict subcellular localization of animal proteins by balancing training dataset and PseAAC

X Cheng, WZ Lin, X Xiao, KC Chou - Bioinformatics, 2019 - academic.oup.com
Motivation A cell contains numerous protein molecules. One of the fundamental goals in cell
biology is to determine their subcellular locations, which can provide useful clues about their …

pLoc_bal-mEuk: predict subcellular localization of eukaryotic proteins by general PseAAC and quasi-balancing training dataset

KC Chou, X Cheng, X Xiao - Medicinal Chemistry, 2019 - ingentaconnect.com
Background/Objective: Information of protein subcellular localization is crucially important for
both basic research and drug development. With the explosive growth of protein sequences …

Proteomic characterization of outer membrane vesicles from gut mucosa-derived fusobacterium nucleatum

J Liu, CL Hsieh, O Gelincik, B Devolder, S Sei… - Journal of …, 2019 - Elsevier
Fusobacterium nucleatum is a Gram-negative bacterium commonly found in the oral cavity
and is often involved in periodontal diseases. Recent studies have shown increased F …

Transposon mutagenesis in Chlamydia trachomatis identifies CT339 as a ComEC homolog important for DNA uptake and lateral gene transfer

SD LaBrie, ZE Dimond, KS Harrison, S Baid… - MBio, 2019 - Am Soc Microbiol
Transposon mutagenesis is a widely applied and powerful genetic tool for the discovery of
genes associated with selected phenotypes. Chlamydia trachomatis is a clinically …

Lifestyle of Lactobacillus hordei isolated from water kefir based on genomic, proteomic and physiological characterization

D Xu, J Bechtner, J Behr, L Eisenbach… - International journal of …, 2019 - Elsevier
Water kefir is a traditional fermented beverage made from sucrose, water, kefir granules,
dried or fresh fruits. In our water kefir granules, Lactobacillus (L.) hordei is one of the …

[HTML][HTML] Proteomic analysis of Lactobacillus nagelii in the presence of Saccharomyces cerevisiae isolated from water kefir and comparison with Lactobacillus hordei

J Bechtner, D Xu, J Behr, C Ludwig… - Frontiers in …, 2019 - frontiersin.org
Water kefir is a slightly alcoholic and traditionally fermented beverage, which is prepared
from sucrose, water, kefir grains, and dried or fresh fruits (eg, figs). Lactobacillus (L.) nagelii …