Targeted therapy for advanced thyroid cancer: kinase inhibitors and beyond

ME Cabanillas, M Ryder, C Jimenez - Endocrine reviews, 2019 - academic.oup.com
The treatment of advanced thyroid cancer has undergone rapid evolution in the last decade,
with multiple kinase inhibitor drug approvals for each subtype of thyroid cancer and a …

Radioiodine-refractory thyroid cancer: molecular basis of redifferentiation therapies, management, and novel therapies

M Aashiq, DA Silverman, S Na'ara, H Takahashi… - Cancers, 2019 - mdpi.com
Recurrent, metastatic disease represents the most frequent cause of death for patients with
thyroid cancer, and radioactive iodine (RAI) remains a mainstay of therapy for these patients …

[HTML][HTML] Thyroid cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

S Filetti, C Durante, D Hartl, S Leboulleux, LD Locati… - Annals of …, 2019 - Elsevier
This ESMO Clinical Practice Guideline provides updated state-of-the-art recommendations
on management of thyroid cancer (diagnosis, treatment and follow-up), compiled by a …

European perspective on 2015 American Thyroid Association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer …

M Luster, C Aktolun, I Amendoeira, M Barczyński… - Thyroid, 2019 - liebertpub.com
Background: The American Thyroid Association (ATA) management guidelines for patients
with thyroid nodules and differentiated thyroid cancer (DTC) are highly influential practice …

Molecular alterations in thyroid cancer: from bench to clinical practice

E Tirrò, F Martorana, C Romano, SR Vitale, G Motta… - Genes, 2019 - mdpi.com
Thyroid cancer comprises different clinical and histological entities. Whereas differentiated
(DTCs) malignancies are sensitive to radioiodine therapy, anaplastic (ATCs) and medullary …

[PDF][PDF] Therapeutic options for advanced thyroid cancer

A Jayarangaiah, G Sidhu, J Brown… - … journal of clinical …, 2019 - pdfs.semanticscholar.org
Thyroid cancer can be largely classified as well-differentiated, poorly differentiated,
medullary and anaplastic. Differentiated thyroid cancer (DTC) includes follicular and …

PET/CT in thyroid nodule and differentiated thyroid cancer patients. The evidence-based state of the art

A Piccardo, P Trimboli, L Foppiani, G Treglia… - Reviews in Endocrine …, 2019 - Springer
A more conservative approach to the clinical management of thyroid nodules and
differentiated thyroid cancer has recently been proposed by the 2015 ATA guidelines. In this …

LRG‑1 enhances the migration of thyroid carcinoma cells through promotion of the epithelial‑mesenchymal transition by activating MAPK/p38 signaling

Z Ban, J He, Z Tang, L Zhang, Z Xu - Oncology reports, 2019 - spandidos-publications.com
Abstract Leucine‑rich‑alpha‑2‑glycoprotein 1 (LRG‑1) has been reported to be associated
with multiple malignancies. However, its participation in thyroid carcinoma progression …

Long-term outcomes and prognostic factors in patients with differentiated thyroid carcinoma and bone metastases

O Slook, S Levy, I Slutzky-Shraga, G Tsvetov… - Endocrine Practice, 2019 - Elsevier
Objective: This institutional study sought to retrospectively evaluate disease progression and
survival of patients with differentiated thyroid cancer (DTC) and bone metastases (BM) and …

Treatment-related adverse effects with TKIs in patients with advanced or radioiodine refractory differentiated thyroid carcinoma: a systematic review and meta-analysis

ST Yu, JN Ge, JY Luo, ZG Wei, BH Sun… - Cancer management …, 2019 - Taylor & Francis
Background Tyrosine kinase inhibitors (TKIs) have been administered to advanced or radio-
iodine refractory differentiated thyroid carcinoma (RR-DTC) patients for years. We performed …