Inflammation is currently considered a prime target for the development of new stroke
therapies. In the acute phase of ischemic stroke, microglia are activated and then circulating …

Introduction: Spontaneous non-traumatic intracerebral hemorrhage (ICH) is most often
caused by small vessel diseases: deep perforator arteriopathy (hypertensive arteriopathy) or …

The recognition that atherosclerosis is a complex chronic inflammatory disorder mediated
through both adaptive and innate immunity has led to the hypothesis that anticytokine …

The NLRP3 (nucleotide-binding oligomerization domain-like receptor [NLR] family pyrin
domain-containing 3) inflammasome is a member of the NLR family of innate immune cell …

Stroke is a major cause of morbidity and mortality worldwide. Despite the intensive search
for new therapies, hundreds of agents targeting various pathophysiological mechanisms …

The inflammatory response is an unavoidable process and contributes to the destruction of
cerebral tissue during the acute ischemic stroke (AIS) phase and has not been addressed …

The role of immunity in all stages of stroke is increasingly being recognized, from the
pathogenesis of risk factors to tissue repair, leading to the investigation of a range of …

The significant morbidity that accompanies stroke makes it one of the world's most
devastating neurological disorders. Currently, proven effective therapies have been limited …

Infections in the post-acute phase of cerebral ischaemia impede optimal recovery by
exacerbating morbidity and mortality. Our review aims to reconcile the increased infection …

Background and Purpose—The contribution of neuroinflammation and, in particular, the
infiltration of the brain by lymphocytes is increasingly recognized as a substantial …