NF-κB, IκB, and IKK: integral components of immune system signaling

MC Mulero, T Huxford, G Ghosh - Structural immunology, 2019 - Springer
Abstract The NF-κB (Nuclear Factor kappa B) transcription factor plays crucial roles in the
regulation of numerous biological processes including development of the immune system …

[HTML][HTML] The two NF-κB pathways regulating bacterial and WSSV infection of shrimp

C Li, S Wang, J He - Frontiers in immunology, 2019 - frontiersin.org
The outbreak of diseases ordinarily results from the disruption of the balance and harmony
between hosts and pathogens. Devoid of adaptive immunity, shrimp rely largely on the …

[HTML][HTML] Antioxidative, anti-inflammatory, and anti-aging properties of mycosporine-like amino acids: Molecular and cellular mechanisms in the protection of skin-aging

H Kageyama, R Waditee-Sirisattha - Marine Drugs, 2019 - mdpi.com
Prolonged exposure to ultraviolet (UV) radiation causes photoaging of the skin and induces
a number of disorders, including sunburn, fine and coarse wrinkles, and skin cancer risk …

Genome reading by the NF-κB transcription factors

MC Mulero, VYF Wang, T Huxford… - Nucleic acids …, 2019 - academic.oup.com
The NF-κB family of dimeric transcription factors regulates transcription by selectively
binding to DNA response elements present within promoters or enhancers of target genes …

[HTML][HTML] NFκB and kidney injury

N Song, F Thaiss, L Guo - Frontiers in immunology, 2019 - frontiersin.org
The global burden of chronic kidney disease will increase during the next century. As NFκB,
first described more than 30 years ago, plays a major role in immune and non-immune …

[HTML][HTML] The many faces of FKBP51

A Hähle, S Merz, C Meyners, F Hausch - Biomolecules, 2019 - mdpi.com
The FK506-binding protein 51 (FKBP51) has emerged as a key regulator of endocrine stress
responses in mammals and as a potential therapeutic target for stress-related disorders …

[HTML][HTML] Innate immune cells and toll-like receptor–dependent responses at the maternal–fetal interface

A Olmos-Ortiz, P Flores-Espinosa… - International Journal of …, 2019 - mdpi.com
During pregnancy, the placenta, the mother and the fetus exploit several mechanisms in
order to avoid fetal rejection and to maintain an immunotolerant environment throughout …

Influenza M2 protein regulates MAVS-mediated signaling pathway through interacting with MAVS and increasing ROS production

R Wang, Y Zhu, X Lin, C Ren, J Zhao, F Wang, X Gao… - Autophagy, 2019 - Taylor & Francis
Influenza A virus can evade host innate immune response that is involved in several viral
proteins with complicated mechanisms. To date, how influenza A M2 protein modulates the …

RNA–DNA fibers and polygons with controlled immunorecognition activate RNAi, FRET and transcriptional regulation of NF-κB in human cells

W Ke, E Hong, RF Saito, MC Rangel… - Nucleic acids …, 2019 - academic.oup.com
Nucleic acid–based assemblies that interact with each other and further communicate with
the cellular machinery in a controlled manner represent a new class of reconfigurable …

[HTML][HTML] The differences in the proteome profile of cannabidiol-treated skin fibroblasts following UVA or UVB irradiation in 2D and 3D cell cultures

A Gęgotek, S Atalay, P Domingues, E Skrzydlewska - Cells, 2019 - mdpi.com
Cannabidiol (CBD), as the only phytocannabinoid that has no psychoactive effect, has both
antioxidant and anti-inflammatory effects, and thus might be suggested as a cytoprotective …