Gallbladder cancer (GBC) is a form of hepatobiliary malignancy that develops from the
mucosal lining of the gallbladder. The early development of gallbladder cancer is usually …

Introduction: Heritage is the most important risk factor for breast cancer. About 15–20% of
breast cancer is familial, referring to affected women who have one or more first-or second …

The GWAS Catalog delivers a high-quality curated collection of all published genome-wide
association studies enabling investigations to identify causal variants, understand disease …

Stratification of women according to their risk of breast cancer based on polygenic risk
scores (PRSs) could improve screening and prevention strategies. Our aim was to develop …

Polygenic risk scores (PRS) have shown promise in predicting human complex traits and
diseases. Here, we present PRS-CS, a polygenic prediction method that infers posterior …

To further dissect the genetic architecture of colorectal cancer (CRC), we performed whole-
genome sequencing of 1,439 cases and 720 controls, imputed discovered sequence …

Mosaic loss of chromosome Y (LOY) in circulating white blood cells is the most common
form of clonal mosaicism,,,–, yet our knowledge of the causes and consequences of this is …

Venous thromboembolism (VTE) is a significant contributor to morbidity and mortality. To
advance our understanding of the biology contributing to VTE, we conducted a genome …

Abstract The dbPTM (http://dbPTM. mbc. nctu. edu. tw/) has been maintained for over 10
years with the aim to provide functional and structural analyses for post-translational …

Mendelian randomization (MR) has emerged as a major tool for the investigation of causal
relationship among traits, utilizing results from large-scale genome-wide association studies …