Abstract Background Tumor-associated macrophages (TAMs) are known to play important
roles in the initiation and progression of human cancers, as well as in angiogenesis. TAMs …

Aging is a complex process with an impact on essentially all organs. Declined cellular repair
causes increased damage at genomic and proteomic levels upon aging. This can lead to …

A comprehensive understanding of the changes in gene expression in cell types involved in
idiopathic pulmonary fibrosis (IPF) will shed light on the mechanisms underlying the loss of …

Microglial cells, which are highly plastic, immediately respond to any change in the
microenvironment by becoming activated and shifting the phenotype toward neurotoxicity or …

The plasma membrane tetraspan molecule MS4A4A is selectively expressed by
macrophage-lineage cells, but its function is unknown. Here we report that MS4A4A was …

The sphingolipid sphingosine-1-phosphate (S1P) is produced by sphingosine kinases to
either signal through intracellular targets or to activate a family of specific G-protein-coupled …

Adipose tissue macrophages (ATMs) are crucial for maintaining adipose tissue homeostasis
and mediating obesity-induced metabolic abnormalities, including prediabetic conditions …

We are living through an unprecedented accumulation of data on gene expression by
macrophages, reflecting their origin, distribution, and localization within all organs of the …

Cell-based technologies are used as a therapeutic strategy in spinal cord injury (SCI).
Mesenchymal stem cells (MSCs), which secrete various neurotrophic factors and cytokines …

Significance: Wound healing is a complex and dynamic series of events influenced by a
variety of intrinsic and extrinsic factors. Problematic wounds, particularly chronic wounds …