Background: Venous thromboembolism (VTE) is a common source of perioperative
morbidity and mortality. Objective: These evidence-based guidelines from the American …

Initial Care of the Severely Injured Patient Trauma care has improved owing to interventions
first used on the battlefield. Recent advances include the use of tourniquets, permissive …

Background Severe traumatic injury continues to present challenges to healthcare systems
around the world, and post-traumatic bleeding remains a leading cause of potentially …

Background Septic coagulopathy represents a very dynamic disease entity, tilting from initial
hypercoagulability towards a subsequent hypocoagulable disease state, entitled overt …

METHODS Rotational thrombelastometry, rTEG, and clinical data were prospectively
collected on trauma patients admitted to an urban Level I trauma center from 2010 to 2016 …

Objective To investigate the efficacy and safety of tranexamic acid (TXA) in the reduction of
bleeding and the need for transfusion in elderly intertrochanteric fracture patients. Methods …

Although pregnant trauma patients present infrequently to the emergency department (ED),
it is one of the most common contributors to maternal and fetal morbidity and mortality. 1–8 …

Background: A massive hemorrhage protocol (MHP) enables rapid delivery of blood
components in a patient who is exsanguinating pending definitive hemorrhage control, but …

The relationship between malignancy and coagulopathy is one that is well documented yet
incompletely understood. Clinicians have attempted to quantify the hypercoagulable state …

Introduction Tranexamic acid (TXA) is one of the debated therapies in the management of
traumatic brain injury (TBI). We conducted this study to evaluate the benefits of TXA in TBI on …