Activating the nucleic acid-sensing machinery for anticancer immunity

T Medler, JM Patel, A Alice, JR Baird, HM Hu… - International review of …, 2019 - Elsevier
Nucleic acid sensing pathways have likely evolved as part of a broad pathogen sensing
strategy intended to discriminate infectious agents and initiate appropriate innate and …

Modulation of CRTh2 expression on allergen‐specific T cells following peptide immunotherapy

CD Rudulier, E Tonti, E James, WW Kwok, M Larché - Allergy, 2019 - Wiley Online Library
Background Allergen immunotherapy using synthetic peptide T‐cell epitopes (Cat‐PAD)
from the major cat allergen Fel d 1 has been shown, in allergen exposure studies, to …

An investigation into the phenotype, function and immunomodulatory properties of in vitro expanded iNKT cells

C Dempsey - 2019 - etheses.bham.ac.uk
Invariant natural killer T (iNKT) cells are endowed with features of both innate and adaptive
immunity. They are activated by the recognition of glycolipid agonists presented by CD1d …