Zika virus during pregnancy: From maternal exposure to congenital Zika virus syndrome

L Pomar, D Musso, G Malinger, M Vouga… - Prenatal …, 2019 - Wiley Online Library
What is already known about the topic? The Zika virus (ZIKV) emergence and its
consequences during pregnancy led to an increasing number of data about the maternal …

Human urban arboviruses can infect wild animals and jump to sylvatic maintenance cycles in South America

LTM Figueiredo - Frontiers in cellular and infection microbiology, 2019 - frontiersin.org
The present study shows that the most prominent human arboviruses worldwide (dengue
viruses 1, 2, 3, and 4, Chikungunya virus, and Zika virus) can infect wild animals and transfer …

Association of infants exposed to prenatal Zika virus infection with their clinical, neurologic, and developmental status evaluated via the general movement …

C Einspieler, F Utsch, P Brasil, CYP Aizawa… - JAMA network …, 2019 - jamanetwork.com
Importance There is an urgent need to assess neurodevelopment in Zika virus (ZIKV)–
exposed infants. Objectives To perform general movement assessment (GMA) at 9 to 20 …

[HTML][HTML] Travel surveillance and genomics uncover a hidden Zika outbreak during the waning epidemic

ND Grubaugh, S Saraf, K Gangavarapu, A Watts… - Cell, 2019 - cell.com
The Zika epidemic in the Americas has challenged surveillance and control. As the epidemic
appears to be waning, it is unclear whether transmission is still ongoing, which is …

[HTML][HTML] Cross-protection of dengue virus infection against congenital Zika syndrome, Northeastern Brazil

C Pedroso, C Fischer, M Feldmann… - Emerging infectious …, 2019 - ncbi.nlm.nih.gov
The Zika virus outbreak in Latin America resulted in congenital malformations, called
congenital Zika syndrome (CZS). For unknown reasons, CZS incidence was highest in …

Clinical and neurodevelopmental features in children with cerebral palsy and probable congenital Zika

A Carvalho, C Brites, G Mochida, P Ventura… - Brain and …, 2019 - Elsevier
Objective To describe the neurological and neurodevelopmental features at 1 year of age in
children with cerebral palsy (CP) related to probable congenital Zika (CZ), followed in a …

Zika virus impairs neurogenesis and synaptogenesis pathways in human neural stem cells and neurons

L Rosa-Fernandes, FR Cugola, FB Russo… - Frontiers in cellular …, 2019 - frontiersin.org
Growing evidences have associated Zika virus (ZIKV) infection with congenital
malformations, including microcephaly. Nonetheless, signaling mechanisms that promote …

Zika virus and the nonmicrocephalic fetus: why we should still worry

CL Walker, MTE Little, JA Roby, B Armistead… - American journal of …, 2019 - Elsevier
Zika virus is a mosquito-transmitted flavivirus and was first linked to congenital microcephaly
caused by a large outbreak in northeastern Brazil. Although the Zika virus epidemic is now …

Zika virus infection at mid-gestation results in fetal cerebral cortical injury and fetal death in the olive baboon

S Gurung, N Reuter, A Preno, J Dubaut… - PLoS …, 2019 - journals.plos.org
Zika virus (ZIKV) infection during pregnancy in humans is associated with an increased
incidence of congenital anomalies including microcephaly as well as fetal death and …

The African strain of Zika virus causes more severe in utero infection than Asian strain in a porcine fetal transmission model

D Udenze, I Trus, N Berube, V Gerdts… - Emerging microbes & …, 2019 - Taylor & Francis
Studies in mice showed that African Zika virus (ZIKV) strains cause more damage in
embryos. These studies, however, were limited to the mouse-adapted African MR766 strain …