The role of adipose tissue and adipokines in sepsis: inflammatory and metabolic considerations, and the obesity paradox

I Karampela, GS Christodoulatos, M Dalamaga - Current obesity reports, 2019 - Springer
Purpose Sepsis has become a global health problem with rising incidence and high
mortality, creating a substantial social and economic burden. Early diagnosis and treatment …

Glycemic control in the intensive care unit: a control systems perspective

JG Chase, B Benyo, T Desaive - Annual Reviews in Control, 2019 - Elsevier
Computers and automation have revolutionised quality and productivity in many industries,
but not in medicine. Healthcare costs are thus growing beyond the ability of society to pay for …

A randomized controlled trial on the safety and efficacy of exenatide therapy for the inpatient management of general medicine and surgery patients with type 2 …

M Fayfman, RJ Galindo, DJ Rubin, DL Mize… - Diabetes …, 2019 - Am Diabetes Assoc
OBJECTIVE This multicenter, open-label, randomized trial examined the safety and efficacy
of exenatide alone or in combination with basal insulin in non–critically ill patients with type …

[HTML][HTML] Association of multiple glycemic parameters at intensive care unit admission with mortality and clinical outcomes in critically ill patients

P Bellaver, AF Schaeffer, DP Dullius, MV Viana… - Scientific Reports, 2019 - nature.com
The aim of the present study was to investigate the association of multiple glycemic
parameters at intensive care unit (ICU) admission with outcomes in critically ill patients …

[HTML][HTML] Percentage of time in range 70 to 139 mg/dL is associated with reduced mortality among critically ill patients receiving IV insulin infusion

MJ Lanspa, JS Krinsley, AM Hersh, EL Wilson… - Chest, 2019 - Elsevier
Background In addition to hyperglycemia, hypoglycemia, and glycemic variability, reduced
time in targeted blood glucose range (TIR) is associated with increased risk of death in …

Association of inpatient glucose measurements with amputations in patients hospitalized with acute diabetic foot

S Peled, R Pollack, O Elishoov, A Haze… - The Journal of Clinical …, 2019 - academic.oup.com
Context The association of inpatient glucose measurements with amputations in patients
admitted with acute diabetic foot has not been described. Objective To evaluate the …

Management of subarachnoid hemorrhage

B Boling, TR Groves - Critical Care Nurse, 2019 - AACN
Subarachnoid hemorrhage is an often devastating intracranial hemorrhage resulting from
acute bleeding into the subarachnoid space. Although its overall incidence is less than that …

Glucose management technologies for the critically ill

PD Salinas, CE Mendez - Journal of diabetes science and …, 2019 - journals.sagepub.com
Hyperglycemia is common in the intensive care unit (ICU) both in patients with and without a
previous diagnosis of diabetes. The optimal glucose range in the ICU population is still a …

Is intensive insulin therapy the scapegoat for or cause of hypoglycaemia and poor outcome?

V Uyttendaele, JL Knopp, GM Shaw, T Desaive… - IFAC Journal of Systems …, 2019 - Elsevier
In 2009, the NICE-SUGAR study became a reference supporting the use of higher glycaemic
target bands for glycaemic control. The important increased risk of hypoglycaemia and …

[HTML][HTML] Risk factors of intraoperative dysglycemia in elderly surgical patients

C Knaak, T Wollersheim, R Mörgeli… - … Journal of Medical …, 2019 - ncbi.nlm.nih.gov
BACKGROUNDː Dysglycemia is associated with adverse outcome including increased
morbidity and mortality in surgical patients. Acute insulin resistance due to the surgical …