Critical limb ischemia (CLI) is the advanced stage of peripheral artery disease spectrum and
is defined by limb pain or impending limb loss because of compromised blood flow to the …

The hemodynamic definition of critical limb ischemia (CLI) has evolved over time but
remains controversial. We compared the prediction of major amputation by 3 hemodynamic …

Purpose Despite high amputation rates, data on patient-reported outcomes is scarce in the
elderly population with critical limb ischemia. The aim of this study was to provide mortality …

Purpose: The aim of this study is to evaluate plasma biomarkers as predictors for peripheral
arterial disease (PAD). Materials and methods: Prospective longitudinal cohort study of …

Abnormal, persistent inflammation after bypass surgery could prevent healing of an
ischaemic foot lesion. In 37 patients with peripheral arterial disease (PAD)(Rutherford Grade …

Background A simpler method for detecting atherosclerosis obliterans is required in the
clinical setting. Laser Doppler flowmetry (LDF) is easy to perform and can accurately detect …

Cell therapies to treat critical limb ischaemia have demonstrated only modest results in
clinical trials, and this has been partly attributed to poor cell retention following their delivery …

Abstract Patients with Severe Limb Ischemia (SLI) have a high risk of amputation and
mortality. Here, we investigated a panel of serum biomarkers with the aim of identifying …

Critical limb ischemia (CLI) is a serious condition that entails a high risk of lower limb
amputation. Despite revascularization being the gold-standard therapy, a considerable …

Introduction Severe limb ischaemia (SLI) is the end stage of peripheral arterial occlusive
disease where the viability of the limb is threatened. Around 25% of patients with SLI will …