Quality and quantity control of gene expression by nonsense-mediated mRNA decay
T Kurosaki, MW Popp, LE Maquat - Nature reviews Molecular cell …, 2019 - nature.com
Nonsense-mediated mRNA decay (NMD) is one of the best characterized and most
evolutionarily conserved cellular quality control mechanisms. Although NMD was first found …
evolutionarily conserved cellular quality control mechanisms. Although NMD was first found …
The mRNA repressor TRIM71 cooperates with Nonsense-Mediated Decay factors to destabilize the mRNA of CDKN1A/p21
LA Torres-Fernández, B Jux, M Bille, Y Port… - Nucleic acids …, 2019 - academic.oup.com
Nonsense-mediated decay (NMD) plays a fundamental role in the degradation of premature
termination codon (PTC)-containing transcripts, but also regulates the expression of …
termination codon (PTC)-containing transcripts, but also regulates the expression of …
[HTML][HTML] A role for DIS3L2 over natural nonsense-mediated mRNA decay targets in human cells
PJ da Costa, J Menezes, M Saramago… - Biochemical and …, 2019 - Elsevier
The nonsense-mediated decay (NMD) pathway selectively degrades mRNAs carrying a
premature translation-termination codon but also regulates the abundance of a large …
premature translation-termination codon but also regulates the abundance of a large …
Upf1 regulates neurite outgrowth and branching by transcriptional and post-transcriptional modulation of Arc
HG Ryu, JY Seo, Y Jung, SW Kim, E Kim… - Journal of Cell …, 2019 - journals.biologists.com
ABSTRACT A large number of neuronal proteins must show correct spatiotemporal
localization in order to carry out their critical functions. The mRNA transcript for the …
localization in order to carry out their critical functions. The mRNA transcript for the …
Ribosome recycling factor ABCE1 depletion inhibits nonsense-mediated mRNA decay by promoting stop codon readthrough
Nonsense-mediated mRNA decay (NMD) is an essential post-transcriptional surveillance
pathway in vertebrates that appears to be mechanistically linked with translation termination …
pathway in vertebrates that appears to be mechanistically linked with translation termination …
A role for DIS3L2 over human nonsense-mediated mRNA decay targets
PJ da Costa, J Menezes, M Saramago… - bioRxiv, 2019 - biorxiv.org
The nonsense-mediated decay (NMD) pathway selectively degrades mRNAs carrying a
premature translation-termination codon but also regulates the abundance of a large …
premature translation-termination codon but also regulates the abundance of a large …
Mutations of FUS Cause Aggregation of RNA Binding Proteins, Disruptions in Protein Synthesis, and Dysregulation of Nonsense Mediated Decay
ME Kamelgarn - 2019 - uknowledge.uky.edu
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by
motor neuron death and subsequent muscle atrophy. Approximately 15% of ALS cases are …
motor neuron death and subsequent muscle atrophy. Approximately 15% of ALS cases are …