The role of forkhead box proteins in acute myeloid leukemia

C Gurnari, G Falconi, E De Bellis, MT Voso, E Fabiani - Cancers, 2019 - mdpi.com
Forkhead box (FOX) proteins are a group of transcriptional factors implicated in different
cellular functions such as differentiation, proliferation and senescence. A growing number of …

The potential of retinoids for combination therapy of lung cancer: updates and future directions

SK Tripathi, K Pandey, M Panda, MJ Spinella… - Pharmacological …, 2019 - Elsevier
Lung cancer is the most common cancer-related death worldwide. Natural compounds have
shown high biological and pharmaceutical relevance as anticancer agents. Retinoids are …

Activation of NF‐κB signaling pathway during HCG‐induced VEGF expression in luteal cells

Z Zhang, Y Huang, J Zhang, Z Liu, Q Lin… - Cell Biology …, 2019 - Wiley Online Library
Vascular endothelial growth factor (VEGF) plays an essential role in luteal angiogenesis, the
present study therefore utilized luteal cells cultured in vitro to further investigate the …

Retinoids induce antagonism between FOXO3A and FOXM1 transcription factors in human oral squamous cell carcinoma (OSCC) cells

K Osei-Sarfo, LJ Gudas - PLoS One, 2019 - journals.plos.org
To gain a greater understanding of oral squamous cell carcinoma (OSCC) we investigated
the actions of all-trans-retinoic acid (RA; a retinoid), bexarotene (a pan-RXR agonist), and …

Mechanism of action of isotretinoin

BC Melnik - Retinoids in dermatology, 2019 - taylorfrancis.com
Systemic isotretinoin is the most efficient treatment option for the management of severe
forms of acne vulgaris, especially nodulocystic acne. Apoptosis not only explains …