Provocative questions in osteosarcoma basic and translational biology: A report from the Children's Oncology Group
Patients who are diagnosed with osteosarcoma (OS) today receive the same therapy that
patients have received over the last 4 decades. Extensive efforts to identify more effective or …
patients have received over the last 4 decades. Extensive efforts to identify more effective or …
Challenges and opportunities for childhood cancer drug development
PJ Houghton, RT Kurmasheva - Pharmacological reviews, 2019 - ASPET
Cancer in children is rare with approximately 15,700 new cases diagnosed in the United
States annually. Through use of multimodality therapy (surgery, radiation therapy, and …
States annually. Through use of multimodality therapy (surgery, radiation therapy, and …
[HTML][HTML] Dodging the bullet: therapeutic resistance mechanisms in pediatric cancers
N Shah - Cancer Drug Resistance, 2019 - ncbi.nlm.nih.gov
While advances in the treatment of pediatric cancers have improved survival to> 80% across
all tumor types, drug resistance continues to limit survival for a considerable number of …
all tumor types, drug resistance continues to limit survival for a considerable number of …
[HTML][HTML] A retrospective clinicopathological study of osteosarcoma patients with metachronous metastatic relapse
J Bao, J Zeng, C Song, H Yu, Q Shi, W Mai… - Journal of …, 2019 - ncbi.nlm.nih.gov
Purpose: Although osteosarcoma patients receive a standardized treatment, metachronous
metastatic relapse still impairs the overall survival (OS). This study aimed to explore the …
metastatic relapse still impairs the overall survival (OS). This study aimed to explore the …
Is estrogen the answer for osteosarcoma?
RD Roberts - Cancer Research, 2019 - AACR
Bone biologists have long understood how estrogen drives osteoclasts to make new bone.
While evidence hinted that a loss of estrogen signals might also play a role in bone-forming …
While evidence hinted that a loss of estrogen signals might also play a role in bone-forming …
[图书][B] Development and Characterization of Osteosarcoma Patient-derived Xenograph Models and Investigation into the Pathogenesis of Osteosarcoma Metastasis
A Koehne - 2019 - search.proquest.com
Osteosarcoma is the most common bone cancer of adolescents with 400 cases diagnosed
annually in the United States. Early metastatic spread to the lungs is a hallmark feature of …
annually in the United States. Early metastatic spread to the lungs is a hallmark feature of …