The life sciences are currently being transformed by an unprecedented wave of
developments in molecular analysis, which include important advances in instrumental …

Context Sex hormone–binding globulin (SHBG) levels are associated with cardiovascular
disease (CVD) risk factors. However, prospective data on the association between SHBG …

Liquid-chromatography mass spectrometry is commonly used to identify and quantify
metabolites from biological samples to gain insight into human physiology and pathology …

Blood is a liquid connective tissue with a complex composition that supplies oxygen and
nutrients to cells. It is minimally invasive to obtain and can be used in “omics” technologies …

Background Our previous research revealed that membrane type 1-matrix metalloproteinase
(MT1-MMP) is overexpressed and plays a crucial role in gastric cancer (GC) progression …

The attempt to describe complex diseases by solely genetic determination has not been
successful. There is increasing recognition that the development of disease is often a …

Metabolic profiling of biofluids by nuclear magnetic resonance (NMR) spectroscopy serves
as an important tool in disease characterization, and its accuracy largely depends on the …

NMR-based quantification of human lipoprotein (sub) classes is a powerful high-throughput
method for medical diagnostics. We evaluated select proton NMR signals of serum …

Background A rare and benign cause of isolated aspartate aminotransferase (AST) increase
is due to the presence of macro aspartate aminotransferase (macro‐AST). Macro‐AST is not …

Plasma biochemical enzymes are commonly assayed as part of a diagnostic evaluation for
zoological species, but their interpretation is complicated by a lack of knowledge about …