Recent advances in aptamer discovery and applications

Y Zhang, BS Lai, M Juhas - Molecules, 2019 - mdpi.com
Aptamers are short, single-stranded DNA, RNA, or synthetic XNA molecules that can be
developed with high affinity and specificity to interact with any desired targets. They have …

Inside the black box: what makes SELEX better?

N Komarova, A Kuznetsov - Molecules, 2019 - mdpi.com
Aptamers are small oligonucleotides that are capable of binding specifically to a target, with
impressive potential for analysis, diagnostics, and therapeutics applications. Aptamers are …

Aptasensors as a new sensing technology developed for the detection of MUC1 mucin: A review

M Yousefi, S Dehghani, R Nosrati, H Zare… - Biosensors and …, 2019 - Elsevier
Abstract Mucin 1 protein (MUC1) is a membrane-associated glycoprotein overexpressed in
the majority of human malignancies and considered as a predominant protein biomarker in …

Evolution of multi-functional capillary electrophoresis for high-efficiency selection of aptamers

C Zhu, G Yang, M Ghulam, L Li, F Qu - Biotechnology advances, 2019 - Elsevier
Aptamers have drawn considerable attention as newly emerging molecular recognition
elements in clinical diagnostics, drug delivery, therapeutics, environmental monitoring, and …

High-efficiency selection of aptamers for bovine lactoferrin by capillary electrophoresis and its aptasensor application in milk powder

C Zhu, L Li, G Yang, M Irfan, Z Wang, S Fang, F Qu - Talanta, 2019 - Elsevier
Capillary electrophoresis-based systematic evolution of ligands by exponential enrichment
(CE-SELEX) is a high-efficient technique for aptamers selection, and has been evolved into …

Electrochemical-based biosensors for detection of Mycobacterium tuberculosis and tuberculosis biomarkers

B Golichenari, R Nosrati, A Farokhi-Fard… - Critical reviews in …, 2019 - Taylor & Francis
Early detection of tuberculosis (TB) reduces the interval between infection and the beginning
of treatment. However, commercially available tests cannot discriminate between BCG …

A bottom-up approach for developing aptasensors for abused drugs: biosensors in forensics

E Celikbas, S Balaban, S Evran, H Coskunol, S Timur - Biosensors, 2019 - mdpi.com
Aptamer-based point-of-care (POC) diagnostics platforms may be of substantial benefit in
forensic analysis as they provide rapid, sensitive, user-friendly, and selective analysis tools …

Challenges in the electrochemical (bio) sensing of nonelectroactive food and environmental contaminants

G Moro, K De Wael, LM Moretto - Current Opinion in Electrochemistry, 2019 - Elsevier
Electrochemical detection of nonelectroactive contaminants can be successfully faced via
the use of indirect detection strategies. These strategies can provide sensitive and selective …

[HTML][HTML] Screening of aptamers and their potential application in targeted diagnosis and therapy of liver cancer

GQ Zhang, LP Zhong, N Yang… - World journal of …, 2019 - ncbi.nlm.nih.gov
Aptamers are a class of single oligonucleotide molecules (DNA or RNA) that are screened
from random DNA or RNA oligonucleotide chain libraries by the systemic evolution of …

Novel insights into the role of aptamers in the fight against cancer

Y Maimaitiyiming, DF Hong, C Yang… - Journal of Cancer …, 2019 - Springer
Purpose Aptamers are a class of single-stranded nucleic acid (DNA or RNA)
oligonucleotides that are screened in vitro by a technique called systematic evolution of …