Saliva is a complex matrix that reflects hormonal, immunological, metabolic and nutritional
state of a person. Moreover, it is considered the most appropriate biological fluid for scientific …

Autoimmune diseases are caused by self-immune responses to autoantigens, which
damage body tissues and severely affect the patient's quality of life. Therapeutic drugs are …

Background Mononuclear cell infiltration of exocrine glands, production of Ro/SSA and
La/SSB autoantibodies, along with oral and ocular dryness, are characteristic features of …

Background This proof of concept study was aimed at characterizing novel salivary
biomarkers specific for different subsets in primary Sjögren's syndrome (pSS) in order to …

In the era of personalised medicine new biomarkers are required to early diagnose
Sjögren's syndrome (SS), to define different disease subsets and to direct patients' clinical …

Primary Sjögren's syndrome (pSS) is a chronic systemic autoimmune disease that affects
exocrine glands. To study the molecular mechanism and identify crucial genes/pathways in …

Primary Sjögren's syndrome (pSS) is a common chronic autoimmune disease characterized
by a high prevalence of autoantibodies and lymphocyte-mediated exocrine gland damage …

The proper diagnosis is a critical factor to reduce further disturbances at the early stage of
the disease and plays an important role in increasing the success rate of the therapy. The …

Objective: To investigate the risk of chronic rhinosinusitis (CRS) among patients with
Sjögren's syndrome (SS). Method: A total of 18,723 patients diagnosed with SS between …

The preanalytical phase of saliva proteomics/peptidomics, which includes sample collection,
handling, and storage, represents a major challenge for any researcher that envisions …