New insights into protein–DNA binding specificity from hydrogen bond based comparative study
M Lin, J Guo - Nucleic acids research, 2019 - academic.oup.com
Abstract Knowledge of protein–DNA binding specificity has important implications in
understanding DNA metabolism, transcriptional regulation and developing therapeutic …
understanding DNA metabolism, transcriptional regulation and developing therapeutic …
The intrinsic structure of poly (A) RNA determines the specificity of Pan2 and Caf1 deadenylases
Abstract The 3′ poly (A) tail of messenger RNA is fundamental to regulating eukaryotic
gene expression. Shortening of the poly (A) tail, termed deadenylation, reduces transcript …
gene expression. Shortening of the poly (A) tail, termed deadenylation, reduces transcript …
[HTML][HTML] Bispecific forkhead transcription factor FoxN3 recognizes two distinct motifs with different DNA shapes
Transcription factors (TFs) control gene expression by binding DNA recognition sites in
genomic regulatory regions. Although most forkhead TFs recognize a canonical forkhead …
genomic regulatory regions. Although most forkhead TFs recognize a canonical forkhead …
[HTML][HTML] The patchy distribution of restriction–modification system genes and the conservation of orphan methyltransferases in halobacteria
Restriction–modification (RM) systems in bacteria are implicated in multiple biological roles
ranging from defense against parasitic genetic elements, to selfish addiction cassettes, and …
ranging from defense against parasitic genetic elements, to selfish addiction cassettes, and …
[HTML][HTML] Selection of DNA cleavage sites by topoisomerase II results from enzyme-induced flexibility of DNA
Topoisomerase II cleaves DNA at preferred sequences with different efficiencies; however,
the mechanism of cleavage site selection is not known. Here we used single-molecule …
the mechanism of cleavage site selection is not known. Here we used single-molecule …
Recognition of poly (A) RNA through its intrinsic helical structure
TTL Tang, LA Passmore - Cold Spring Harbor symposia on …, 2019 - symposium.cshlp.org
Abstract The polyadenosine (poly (A)) tail, which is found on the 3′ end of almost all
eukaryotic messenger RNAs (mRNAs), plays an important role in the posttranscriptional …
eukaryotic messenger RNAs (mRNAs), plays an important role in the posttranscriptional …
Structural insights into interactions between viral suppressor of RNA silencing protein p19 mutants and small RNA s
Viral suppressors of RNA silencing (VSRS s) are a diverse group of viral proteins that have
evolved to disrupt eukaryotic RNA silencing pathways, thereby contributing to viral …
evolved to disrupt eukaryotic RNA silencing pathways, thereby contributing to viral …
Fixation of atmospheric CO2 and recognition of anions/hydrated anions: Differential binding mode in protonated vs. neutral tripodal urea/thiourea receptors
Abstract Tris-(2-aminoethyl) amine (Tren) based tripodal thiourea (L 1 and L 2) and urea (L
3) receptors are reported. L 1 efficiently fix atmospheric CO 2 as CO 3 2–in presence of the …
3) receptors are reported. L 1 efficiently fix atmospheric CO 2 as CO 3 2–in presence of the …
DNA shape complements sequence-based representations of transcription factor binding sites
The position weight matrix (PWM) has long been a useful tool for describing variation in the
composition of regions of DNA such as transcription factor (TF) binding sites. It is difficult …
composition of regions of DNA such as transcription factor (TF) binding sites. It is difficult …