Exosomes are small, single-membrane, secreted organelles of∼ 30 to∼ 200 nm in
diameter that have the same topology as the cell and are enriched in selected proteins …

Exosomes are endosomal-derived vesicles, playing a major role in cell-to-cell
communication. Multiple cells secret these vesicles to induce and inhibit different cellular …

Tumor cells utilize different strategies to communicate with neighboring tissues for facilitating
tumor progression and invasion, one of these strategies has been shown to be the release …

Since the tumor is extremely heterogeneous, a single biomarker cannot reflect the exact
symptoms of the disease or its stage. Exosomes are biomarker reservoirs that provide …

The αvβ3 integrin has been shown to promote aggressive phenotypes in many types of
cancers, including prostate cancer. We show that GFP-labeled αvβ3 derived from cancer …

Abstract c-Src is a membrane-associated tyrosine kinase that has key roles in the signaling
transduction that controls cell growth, adhesion, and migration. In the early stage of …

Human liver stem‐like cells (HLSC) and derived extracellular vesicles (EVs) were previously
shown to exhibit anti‐tumor activity. In our study, we investigated whether HLSC‐derived …

Exosomes are small membrane vesicles that measure 20 to 100 nm in diameter and are
released by many cell types, including lymphocytes, dendritic cells (DCs) and tumor cells. As …

Ligand-activated plasma membrane receptors follow pathways of endocytosis through the
endosomal sorting apparatus. Receptors cluster in clathrin-coated pits that bud inwards and …

Abstract Cancer Stem Cells (CSCs) are self-renewing cancer cells responsible for
expansion of the malignant mass in a dynamic process shaping the tumor …