Matrix Metalloproteinases: A challenging paradigm of cancer management
Matrix metalloproteinases (MMPs) are members of zinc-dependent endopeptidases
implicated in a variety of physiological and pathological processes. Over the decades …
implicated in a variety of physiological and pathological processes. Over the decades …
Interplay between miRNAs and host genes and their role in cancer
MicroRNAs (miRNAs) are small endogenous non-coding functional RNAs that post-
transcriptionally regulate gene expression. They play essential roles in nearly all biological …
transcriptionally regulate gene expression. They play essential roles in nearly all biological …
Synthetic circular multi-miR sponge simultaneously inhibits miR-21 and miR-93 in esophageal carcinoma
Z Wang, KE Ma, Y Cheng, JM Abraham, X Liu… - Laboratory …, 2019 - nature.com
MicroRNAs (miRs) are post-transcriptional regulators involved in the initiation and
progression of many tumors. Recently, naturally occurring circular RNAs (circRNAs) have …
progression of many tumors. Recently, naturally occurring circular RNAs (circRNAs) have …
miRNA expression changes during the course of neoadjuvant bevacizumab and chemotherapy treatment in breast cancer
EM Lindholm, M Ragle Aure, MH Haugen… - Molecular …, 2019 - Wiley Online Library
One of the hallmarks of cancer is sustained angiogenesis. Favorable results have been
reported in some breast cancer (BC) patients receiving antiangiogenic therapy with …
reported in some breast cancer (BC) patients receiving antiangiogenic therapy with …
Circulating miRNAs in untreated breast cancer: an exploratory multimodality morpho-functional study
The aim of this study was to identify new disease-related circulating miRNAs with high
diagnostic accuracy for breast cancer (BC) and to correlate their deregulation with the …
diagnostic accuracy for breast cancer (BC) and to correlate their deregulation with the …
Identification of serum miR-30a-5p as a diagnostic and prognostic biomarker in colorectal cancer
Y Sun, B Yang, M Lin, H Yu, H Chen… - Cancer …, 2019 - content.iospress.com
BACKGROUND: Circulating microRNAs (miRNAs) have become increasingly appreciated in
the diagnosis and prognosis of colorectal cancer (CRC). OBJECTIVE: The aim of this study …
the diagnosis and prognosis of colorectal cancer (CRC). OBJECTIVE: The aim of this study …
miR-182-5p affects human bladder cancer cell proliferation, migration and invasion through regulating Cofilin 1
F Wang, D Wu, Z Xu, J Chen, J Zhang, X Li… - Cancer cell …, 2019 - Springer
Background Human bladder cancer is one of the common malignant tumors, and it mainly
occurs in men. miR-182-5p, a member of miR-183 family, acts as tumor suppressor or …
occurs in men. miR-182-5p, a member of miR-183 family, acts as tumor suppressor or …
Functional micro RNA binding site variants
Y Yuan, JB Weidhaas - Molecular oncology, 2019 - Wiley Online Library
Germline single nucleotide polymorphisms are one of the most common genetic variations.
Polymorphisms that cause nonsynonymous mutations in gene coding regions are known to …
Polymorphisms that cause nonsynonymous mutations in gene coding regions are known to …
NCKAP1 improves patient outcome and inhibits cell growth by enhancing Rb1/p53 activation in hepatocellular carcinoma
X Zhong, A Kan, Y Ling, L Lu, J Mei, W Wei, S Li… - Cell death & …, 2019 - nature.com
In our previous report, we identified miR-34c-3p as an independent factor contributing to the
carcinogenesis of hepatocellular carcinoma (HCC) by targeting NCK Associated Protein 1 …
carcinogenesis of hepatocellular carcinoma (HCC) by targeting NCK Associated Protein 1 …
Altered expression of miR-181 affects cell fate and targets drug resistance-related mechanisms
C Braicu, D Gulei, L Raduly, A Harangus… - Molecular aspects of …, 2019 - Elsevier
MicroRNAs (miRNAs) are non-coding transcripts which regulate genetic and epigenetic
events by interfering with mRNA translation. miRNAs are involved in regulation of cell fate …
events by interfering with mRNA translation. miRNAs are involved in regulation of cell fate …