Antimicrobial resistance (AMR) is a multifaceted complex problem with momentous
consequences for individuals as well as health-care systems. Understanding the gravity of …

The electrochemical aptamer-based (E-AB) sensing platform appears to be a convenient
(rapid, single-step, and calibration-free) and modular approach to measure concentrations …

The focus of this research was to synthesize novel clay-biochar composites by incorporating
montmorillonite (MMT) and red earth (RE) clay materials in a municipal solid waste (MSW) …

Objective To provide a review on the current use of antimicrobials with a discussion on the
pharmacokinetic and pharmacodynamic profiles of antimicrobials in critically ill patients, the …

Few bacteria are resistant to tetracycline and can even biodegrade tetracycline in the
environment. In this study, we isolated a bacterium Pandoraea sp. XY-2, which could …

Background Thrombocytopenia may be a dose-dependent adverse effect of linezolid
therapy. Objectives To assess whether proactive therapeutic drug monitoring (TDM) could …

Objectives: Describe the mechanism of action of the aminoglycosides. Outline the
indications for different aminoglycosides. Summarize the adverse effects and monitoring …

Background: Adequate antibiotic treatment is a prerequisite for the successful treatment of
systemic infections. Based on accumulating scientific evidence, a fixed dosage regimen can …

Background Antibiotic exposure in intensive care patients with sepsis is frequently
inadequate and is associated with poorer outcomes. Antibiotic dosing is challenging in the …

Sepsis and septic shock exhibit a rapid course and a high fatality rate. Antibiotic treatment is
time-critical and precise knowledge of the antibiotic concentration during the patients' …