Background and objectives Obesity is associated with metabolic dysfunction and over
nutrition. Increased body mass index and obesity are strongly amalgamated with changes in …

Growing preclinical evidence shows that short-term fasting (STF) protects from toxicity while
enhancing the efficacy of a variety of chemotherapeutic agents in the treatment of various …

Acromegaly is characterized by chronic overproduction of growth hormone (GH) that leads
to insulin resistance, glucose intolerance and, ultimately, diabetes. The GH-induced …

The exact physiological basis of acute growth hormone (GH) suppression by oral glucose is
not fully understood. Glucose-mediated increase in hypothalamic somatostatin seems to be …

Background The response to first-generation somatostatin receptor ligands (SRLs) treatment
in acromegaly correlates with expression of somatostatin receptor subtype 2 (SSTR2) …

Background: Due to high content of fructose, honey has been introduced as a suitable
natural sweetener for patients with type 2 diabetes. We investigated the effect of honey …

Purpose To explore the effects of pegvisomant (PEGV) on glucose metabolism in patients
with acromegaly within ACROSTUDY, an international, observational, prospective safety …

An adrenal incidentaloma (AI) is an adrenal mass incidentally found via a radiological
modality, independent of an endocrinological investigation. In this review, we aimed to …

Evolutionally conserved in all mammalians, the release of GH occurs in a rhythmic pattern,
characterized by several dominant surges (pulsatile GH) with tonic low inter-pulse levels …

Context Hepatokines have emerged as potential mediators of obesity-associated
comorbidities, such as type 2 diabetes, cardiovascular disease, fractures, and central …