Skeletal and extraskeletal actions of vitamin D: current evidence and outstanding questions

R Bouillon, C Marcocci, G Carmeliet, D Bikle… - Endocrine …, 2019 - academic.oup.com
The etiology of endemic rickets was discovered a century ago. Vitamin D is the precursor of
25-hydroxyvitamin D and other metabolites, including 1, 25 (OH) 2D, the ligand for the …

Current vitamin D status in European and Middle East countries and strategies to prevent vitamin D deficiency: a position statement of the European Calcified Tissue …

P Lips, KD Cashman, C Lamberg-Allardt… - European journal of …, 2019 - academic.oup.com
Vitamin D deficiency (serum 25-hydroxyvitamin D (25 (OH) D)< 50 nmol/L or 20 ng/mL) is
common in Europe and the Middle East. It occurs in< 20% of the population in Northern …

[HTML][HTML] Vitamin D and health-The missing vitamin in humans

SW Chang, HC Lee - Pediatrics & Neonatology, 2019 - Elsevier
Severe vitamin D deficiency may cause rickets in infants or children and osteomalacia in
adults, though it is now uncommon in developed countries. However, subclinical vitamin D …

Vitamin D testing and treatment: a narrative review of current evidence

S Pilz, A Zittermann, C Trummer… - Endocrine …, 2019 - ec.bioscientifica.com
Vitamin D testing and treatment is a subject of controversial scientific discussions, and it is
challenging to navigate through the expanding vitamin D literature with heterogeneous and …

Controversies in vitamin D: summary statement from an international conference

A Giustina, RA Adler, N Binkley… - The Journal of …, 2019 - academic.oup.com
Context Vitamin D is classically recognized as a regulator of calcium and phosphorus
metabolism. Recent advances in the measurement of vitamin D metabolites, diagnosis of …

The role of vitamin D in inflammatory bowel disease: mechanism to management

J Fletcher, SC Cooper, S Ghosh, M Hewison - Nutrients, 2019 - mdpi.com
Vitamin D has been linked to human health benefits that extend far beyond its established
actions on calcium homeostasis and bone metabolism. One of the most well studied facets …

Vitamin D binding protein and the biological activity of vitamin D

RF Chun, A Shieh, C Gottlieb, V Yacoubian… - Frontiers in …, 2019 - frontiersin.org
Vitamin D has a long-established role in bone health. In the last two decades, there has
been a dramatic resurgence in research interest in vitamin D due to studies that have shown …

New developments in our understanding of vitamin D metabolism, action and treatment

S Christakos, S Li, J De La Cruz, DD Bikle - Metabolism, 2019 - Elsevier
Although vitamin D has been reported to have pleiotropic effects including effects on the
immune system and on cancer progression, the principal action of vitamin D is the …

Vitamin D and growth hormone in children: a review of the current scientific knowledge

S Esposito, A Leonardi, L Lanciotti, M Cofini… - Journal of Translational …, 2019 - Springer
Background Human growth is a complex mechanism that depends on genetic,
environmental, nutritional and hormonal factors. The main hormone involved in growth at …

Hypovitaminosis D: is it time to consider the use of calcifediol?

R Cesareo, A Falchetti, R Attanasio, G Tabacco… - Nutrients, 2019 - mdpi.com
Hypovitaminosis D is becoming a notable health problem worldwide. A consensus exists
among several different medical societies as to the need for adequate levels of vitamin D for …