ABSTRACT Introduction: Calcium channel blockers (CCBs) comprise a heterogeneous
group of medications that reduce calcium influx and attenuate cellular hyperactivity …

Importance Posttraumatic stress disorder (PTSD) is associated with increased risk of type 2
diabetes (T2D). Improvement in PTSD has been associated with improved self-reported …

Objectives To assess whether a history of major depressive disorder (MDD) in middle-aged
individuals with hypertension influences first-onset cardiovascular disease outcomes …

Background Evidence is increasing that pathways of antihypertensives may have a role in
the pathogenesis of depression. However, how the class of antihypertensives affects …

Background Arterial stiffness may contribute to late-life depression via cerebral
microvascular damage, but evidence is scarce. No longitudinal study has evaluated the …

Background The discovery that voltage-gated calcium channel genes such as CACNA1C
are part of the aetiology of psychiatric disorders has rekindled interest in the therapeutic …

Background Depressive symptoms are common in patients with coronary artery disease
(CAD) and are associated with an unfavourable outcome. Establishing prognostic patient …

Background: Since few studies have investigated the risk of high blood pressure associated
with objective insomnia and self-reported insomnia complaints in major depression, the aim …

Background: Both elevated blood pressure and/or depression increase the risk of
cardiovascular disease and mortality. This study in treated elderly hypertensive patients …

Methods: Using arylamide derivatives as substrates, we fluorometrically analysed the activity
of these enzymes in the left and right frontal cortex of control untreated Wistar–Kyoto (WKY) …