In diseases such as multiple sclerosis (MS), inflammation can injure the myelin sheath that
surrounds axons, a process known as demyelination. The spontaneous regeneration of …

Investigating human oligodendrogenesis and the interaction of oligodendrocytes with
neurons and astrocytes would accelerate our understanding of the mechanisms underlying …

Osmotic demyelination syndrome (ODS) is a disorder of the central myelin that is often
associated with a precipitous rise of serum sodium. Remarkably, while the myelin and …

Glioblastoma (GBM) is a major malignant brain tumor developing in adult brain white matter,
characterized by rapid growth and invasion. GBM cells spread into the contralateral …

Oligodendrocytes are fundamental for the functioning of the nervous system; they participate
in several cellular processes, including axonal myelination and metabolic maintenance for …

Repeated stress induces systemic elevations in glucocorticoid levels. Stress is also
associated with alterations in central nervous system astrocytes and oligodendrocytes that …

Canine distemper virus (CDV) causes a fatal demyelinating leukoencephalitis in young dogs
resembling human multiple sclerosis. Astrocytes are the main cellular target of CDV and …

Although several therapies are approved, none promote re-myelination in multiple sclerosis
(MS) patients, limiting their ability for sustained recovery. Thus, treatment development in MS …

Xiaoshuan enteric-coated capsule (XSEC) is a compound Chinese medicine widely used for
the treatment of ischemic stroke. Enriched environment (EE) is a rehabilitative intervention …

Dental pulp stem cells (DPSCs) are promising for use in neurodegenerative-diseases
because of their neural crest origin. While neuronal differentiation of DPSCs has been …