Analogues of desferrioxamine B (DFOB) with new properties and new functions generated using precursor-directed biosynthesis
Desferrioxamine B (DFOB) is a siderophore native to Streptomyces pilosus biosynthesised
by the DesABCD enzyme cluster as a high affinity Fe (III) chelator. Although DFOB has a …
by the DesABCD enzyme cluster as a high affinity Fe (III) chelator. Although DFOB has a …
Activation of Secondary Metabolite Gene Clusters in Streptomyces clavuligerus by the PimM Regulator of Streptomyces natalensis
Y Martínez-Burgo, J Santos-Aberturas… - Frontiers in …, 2019 - frontiersin.org
Expression of non-native transcriptional activators may be a powerful general method to
activate secondary metabolites biosynthetic pathways. PAS-LuxR regulators, whose …
activate secondary metabolites biosynthetic pathways. PAS-LuxR regulators, whose …
Comparative Genomics and Metabolomics Analyses of Clavulanic Acid-Producing Streptomyces Species Provides Insight Into Specialized Metabolism
NF AbuSara, BM Piercey, MA Moore… - Frontiers in …, 2019 - frontiersin.org
Clavulanic acid is a bacterial specialized metabolite, which inhibits certain serine β-
lactamases, enzymes that inactivate β-lactam antibiotics to confer resistance. Due to this …
lactamases, enzymes that inactivate β-lactam antibiotics to confer resistance. Due to this …
Siderophore profiling of co-habitating soil bacteria by ultra-high resolution mass spectrometry
RM Boiteau, SJ Fansler, Y Farris, JB Shaw… - Metallomics, 2019 - academic.oup.com
The chemical structure of organic molecules profoundly impacts their interactions with metal
ions and mineral phases in soils. Understanding the sources and cycling of metal-chelating …
ions and mineral phases in soils. Understanding the sources and cycling of metal-chelating …
Legonoxamines AB, two new hydroxamate siderophores from the soil bacterium, Streptomyces sp. MA37
Two new siderophores belonging to the hydroxamate class, Legonoxamine A (1) and B (2)
have been isolated from the soil bacterium, Streptomyces sp. MA37, together with one …
have been isolated from the soil bacterium, Streptomyces sp. MA37, together with one …
Complete genome sequences of Streptomyces spp. isolated from disease-suppressive soils
Background Bacteria within the genus Streptomyces remain a major source of new natural
product discovery and as soil inoculants in agriculture where they promote plant growth and …
product discovery and as soil inoculants in agriculture where they promote plant growth and …
A suite of asymmetric citrate siderophores isolated from a marine Shewanella species
JR Carmichael, H Zhou, A Butler - Journal of Inorganic Biochemistry, 2019 - Elsevier
Woodybactins AD are a suite of new fatty acyl siderophores produced by the luminous
marine bacterium Shewanella woodyi MS32. While this bacterium has a set of genes …
marine bacterium Shewanella woodyi MS32. While this bacterium has a set of genes …
An isotopic ratio outlier analysis approach for global metabolomics of biosynthetically talented actinomycetes
Actinomycetes are powerhouses of natural product biosynthesis. Full realization of this
biosynthetic potential requires approaches for recognizing novel metabolites and …
biosynthetic potential requires approaches for recognizing novel metabolites and …
Streptomyces corynorhini sp. nov., isolated from Townsend's big-eared bats (Corynorhinus townsendii)
Four bacterial strains, with the capability of inhibiting Pseudogymnoascus destructans, the
causative agent of white-nose syndrome, were isolated from male Townsend's big-eared …
causative agent of white-nose syndrome, were isolated from male Townsend's big-eared …
Complete Genome Sequence of the Putative Phosphonate Producer Streptomyces sp. Strain I6, Isolated from Indonesian Mangrove Sediment
J Krause, S Ratnakomala, P Lisdiyanti… - Microbiology …, 2019 - Am Soc Microbiol
Streptomyces sp. strain I6 is a novel strain isolated from an Indonesian mangrove sediment
sample. Bioinformatic analysis of the genome sequence of Streptomyces sp. I6 revealed 23 …
sample. Bioinformatic analysis of the genome sequence of Streptomyces sp. I6 revealed 23 …