The role of miRNAs in the invasion and metastasis of cervical cancer
J Wang, L Chen - Bioscience reports, 2019 - portlandpress.com
Cervical cancer (CC) with early metastasis of the primary tumor results in poor prognosis
and poor therapeutic outcomes. MicroRNAs (miRNAs) are small, noncoding RNA molecules …
and poor therapeutic outcomes. MicroRNAs (miRNAs) are small, noncoding RNA molecules …
Genome‐wide association studies and polygenic risk scores for skin cancer: clinically useful yet?
MR Roberts, MM Asgari… - British Journal of …, 2019 - academic.oup.com
Background Genome‐wide association studies (GWAS) have identified thousands of
susceptibility variants, although most have been associated with small individual risk …
susceptibility variants, although most have been associated with small individual risk …
Mendelian Randomization and mediation analysis of leukocyte telomere length and risk of lung and head and neck cancers
Background Evidence from observational studies of telomere length (TL) has been
conflicting regarding its direction of association with cancer risk. We investigated the causal …
conflicting regarding its direction of association with cancer risk. We investigated the causal …
Hereditary prostate cancer–Primetime for genetic testing?
I Heidegger, I Tsaur, H Borgmann, C Surcel… - Cancer treatment …, 2019 - Elsevier
Prostate cancer (PCa) remains the most common cancer in men. The proportion of all PCa
attributable to high-risk hereditary factors has been estimated to 5–15%. Recent landmark …
attributable to high-risk hereditary factors has been estimated to 5–15%. Recent landmark …
[HTML][HTML] Telomerase and telomeres in endometrial cancer
RAA Alnafakh, M Adishesh, L Button, G Saretzki… - Frontiers in …, 2019 - frontiersin.org
Telomeres at the termini of human chromosomes are shortened with each round of cell
division due to the “end replication problem” as well as oxidative stress. During …
division due to the “end replication problem” as well as oxidative stress. During …
[HTML][HTML] Nasopharyngeal cancer in Saudi Arabia: Epidemiology and possible risk factors
Abstract Although, Nasopharyngeal Carcinoma (NPC) is uncommon in Arab countries, but
its incidence is raising due to increased exposure to diverse risk factors. Many of the NPC …
its incidence is raising due to increased exposure to diverse risk factors. Many of the NPC …
TERT rs10069690 polymorphism and cancers risk: A meta‐analysis
G He, T Song, Y Zhang, X Chen… - Molecular genetics & …, 2019 - Wiley Online Library
Background Studies have identified that the telomerase reverse transcriptase (TERT) gene
polymorphism rs10069690 (C> T) is associated with cancer risk, but the results remain …
polymorphism rs10069690 (C> T) is associated with cancer risk, but the results remain …
Cutaneous keratinocyte cancers of the head and neck: epidemiology, risk factors and clinical, dermoscopic and reflectance confocal microscopic features
Keratinocyte cancers are the most common malignancy among people with European
ancestry, and are very common on sun-exposed areas of the head and neck. Incidence is …
ancestry, and are very common on sun-exposed areas of the head and neck. Incidence is …
Investigation of leukocyte telomere length and genetic variants in chromosome 5p15. 33 as prognostic markers in lung cancer
L Kachuri, J Helby, SE Bojesen, DC Christiani… - … Biomarkers & Prevention, 2019 - AACR
Background: Lung cancer remains the leading cause of cancer mortality with relatively few
prognostic biomarkers. We investigated associations with overall survival for telomere length …
prognostic biomarkers. We investigated associations with overall survival for telomere length …
Functional polymorphisms on chromosome 5p15. 33 disturb telomere biology and confer the risk of non‐small cell lung cancer in Chinese population
Y Li, C Xiang, N Shen, L Deng, X Luo… - Molecular …, 2019 - Wiley Online Library
The chromosome 5p15. 33 has been reported as a susceptibility locus for lung cancer.
However, causal variants in this region have not been fully uncovered. In this study, we …
However, causal variants in this region have not been fully uncovered. In this study, we …