Despite advancement in cancer treatment, oral cancer has a poor prognosis and is often
detected at late stage. To overcome these challenges, investigators should search for early …

Resistance to cancer therapy remains a major challenge in clinical oncology. Although the
initial treatment phase is often successful, eventual resistance, characterized by tumour …

The deep and inner beds of solid tumors lack lymphocytic infiltration and are subjected to
various immune escape mechanisms. Reversing immunosuppression deep within the tumor …

Immunotherapy has only limited efficacy against pancreatic ductal adenocarcinoma (PDAC)
due to the presence of an immunosuppressive tumor-associated stroma. Here, we …

Along with surgery and radiotherapy, chemotherapeutic agents belong to the therapeutic
arsenal in cancer treatment. In addition to their direct cytotoxic effects, these agents also …

During the life of a human being, several tons of apoptotic cells and debris are produced.
These apoptotic particles should be cleared quickly and accurately from the body, as they …

Great attention has been attached to explore the association between oral bacteria and oral
cancer. Recently, four common inhabitants of oral cavity, Porphyromonas gingivalis …

T‐cell acute lymphoblastic leukemia (T‐ALL) has a poor prognosis derived from its genetic
heterogeneity, which translates to a high chemoresistance. Recently, our workgroup …

Purines, among most influential molecules, are reported to have essential biological function
by regulating various cell types. A large number of studies have led to the discovery of many …

Complete tumor eradication is the ultimate goal of cancer therapy. However, the majority of
anticancer drugs cause nonimmunogenic cell death and only exert on-site anticancer …