Congenital heart defects are the most common birth anomaly affecting approximately 1% of
births. With improved survival in this population, there is enhanced ability to assess long …

This review presents updated recommendations, based on existing clinical research, for
anesthetic management of strabismus surgery in children. In children, unlike adults, eye …

Background Exposure to anesthetics during early life may impair cognitive functions.
However, the underlying mechanisms remain largely unknown. We set out to determine …

Background Anesthesia may induce neurotoxicity and neurocognitive impairment in young
mice. However, the underlying mechanism remains largely to be determined. Meanwhile …

Epidemiological studies suggest exposures to anesthetic agents and/or sedative drugs
(AASDs) in children under three years old, or pregnant women during the third trimester …

Despite the widespread use of general anesthesia, a growing body of research suggests
that anesthesia exposure early in life may be associated with acute neurotoxicity and lasting …

The mechanism of anesthesia neurotoxicity remains largely to be determined. The effects of
long noncoding RNAs (LncRNAs) on neural differentiation and the underlying mechanisms …

Isoflurane is a commonly used inhalational anesthetic, clinically and in animal experimental
studies. Although it has been reported as safe, recent findings suggest that despite …

Objective The purpose of this study is to uncover the effects of long chain noncoding RNA
(lncRNA) metastasis‐associated lung adenocarcinoma transcript 1 (MALAT1) on …

Attention deficit hyperactivity disorder is a chronic neurodevelopmental disorder, manifesting
primarily as attention deficit, hyperactivity and impulsive behaviour. General anaesthetics …