[HTML][HTML] Alteration of the esophageal microbiota in Barrett's esophagus and esophageal adenocarcinoma

J Lv, L Guo, JJ Liu, HP Zhao, J Zhang… - World journal of …, 2019 - ncbi.nlm.nih.gov
The incidence of esophageal adenocarcinoma (EAC) has increased in recent decades, and
its 5-year survival rate is less than 20%. As a well-established precursor, patients with …

Safety and tolerability of immune checkpoint inhibitors (PD-1 and PD-L1) in cancer

I Baraibar, I Melero, M Ponz-Sarvise, E Castanon - Drug safety, 2019 - Springer
Immunotherapy has emerged in recent years and has revolutionized the treatment of cancer.
Immune checkpoint inhibitors, including anti-cytotoxic T lymphocyte antigen-4 (CTLA-4), anti …

Incidence of pancreatitis with the use of immune checkpoint inhibitors (ICI) in advanced cancers: a systematic review and meta-analysis

J George, D Bajaj, K Sankaramangalam, JW Yoo… - Pancreatology, 2019 - Elsevier
Background Systemic immune side effects including pancreatitis have been reported with
the use of Immune Checkpoint Inhibitors (ICI)(CTLA-4, PD-1 and PDL-1). However, the true …

Management of immune related adverse events induced by immune checkpoint inhibition

A Teufel, T Zhan, N Härtel, J Bornschein, MP Ebert… - Cancer Letters, 2019 - Elsevier
In recent years, immune checkpoint inhibitors (ICIs) were successfully introduced to cancer
therapy and these drugs have already become essential for the treatment of various non …

Clinical Significance of Signs of Autoimmune Colitis in 18F-Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography of 100 Stage-IV Melanoma …

N Lang, J Dick, A Slynko, C Schulz… - …, 2019 - Taylor & Francis
Aim: Autoimmune colitis is a typical and possible severe side effect among patients treated
with ipilimumab. Patients & methods: We prospectively included 100 patients with …

Frequency and imaging features of abdominal immune-related adverse events in metastatic lung cancer patients treated with PD-1 inhibitor

F Alessandrino, S Sahu, M Nishino, AE Adeni… - Abdominal …, 2019 - Springer
Purpose To investigate the frequency and imaging features of radiographically evident
abdominal immune-related adverse events (irAEs) in patients with metastatic non-small-cell …

Immune-related pancreatitis associated with checkpoint blockade in melanoma

J Kohlmann, D Wagenknecht, JC Simon… - Melanoma …, 2019 - journals.lww.com
Recognizing and treating rare checkpoint inhibitor related adverse events may be a clinical
challenge in melanoma therapy. One of rather rare affected organs is the pancreas. Immune …

Focal immunotherapy-induced pancreatitis mimicking metastasis on FDG PET/CT

JP Das, D Halpenny, RK Do… - Clinical Nuclear Medicine, 2019 - journals.lww.com
A 46-year-old man with metastatic lung adenocarcinoma was treated with pembrolizumab.
FDG PET/CT was performed after 3 cycles of treatment and revealed a focal region of …

18F-FDG PET/CT of Multiorgan Sarcoid-Like Reaction During Anti–PD-1 Treatment for Melanoma

WW van Willigen, WR Gerritsen… - Clinical Nuclear …, 2019 - journals.lww.com
We report a case of a 50-year-old woman treated with anti–PD-1 inhibition for metastatic
melanoma. During treatment, extensive and transient histopathologically confirmed sarcoid …