Mast cells and their mediators have been implicated in the pathogenesis of asthma and
allergy for decades. Allergic asthma is a complex chronic lung disease in which several …

abstract Severe asthma in children is associated with significant morbidity. Children with
severe asthma are at increased risk for adverse outcomes including medication-related side …

Asthma is a complex disease with striking disparities across racial and ethnic groups.
Despite its relatively high burden, representation of individuals of African ancestry in asthma …

Previous studies found associations between impairments of immune functions and
exposure to polycyclic aromatic hydrocarbons (PAHs) in ambient air pollution in the US and …

Some basic research has shown that nanomaterials can aggravate allergic asthma.
However, its potential mechanism is insufficient. Based on the research that alumina …

Mast cells (MCs) release pro-inflammatory mediators through a process called
degranulation response. The latter may be induced by several conditions, including antigen …

The aim of precision medicine is setting up targeted therapies for selected patients that
would ideally have high effectiveness and few side effects. This is made possible by …

Mast cells are key players in the inflammatory response with an important role in allergic
reactions and are therefore useful for assessing the risk of anaphylaxis. However, they are …

Background Exposure to diisocyanates is an important cause of occupational asthma (OA)
in the industrialized world. Since OA occurs after long-term exposure to diisocyanates, we …

Aim Our aim was to evaluate the correlation of Adenosine monophosphate challenge test
(AMP‐PCW) results with the patients' subsequent clinical course. Methods We performed a …