Sarcopenia is a loss of muscle mass and function in the elderly that reduces mobility,
diminishes quality of life, and can lead to fall-related injuries, which require costly …

Motor endplates (MEPs) are the important interfaces between peripheral nerves and muscle
fibers. Investigation of the spatial distribution of MEPs could help us better understand …

The β-adrenergic agonists salbutamol and ephedrine have proven to be effective as
therapies for human disorders of the neuromuscular junction, in particular many subsets of …

Mechanical forces regulate muscle development, hypertrophy, and homeostasis. Force-
transmitting structures allow mechanotransduction at the sarcolemma, cytoskeleton, and …

Brachial plexus avulsion (BPA) occurs when the spinal nerve roots are pulled away from the
surface of the spinal cord and disconnects neuronal cell body from its distal downstream …

Myostatin is a negative regulator of muscle growth and metabolism and its inhibition in mice
improves insulin sensitivity, increases glucose uptake into skeletal muscle, and decreases …

Abstract Background Niemann-Pick disease type A (NPDA), a disease caused by mutations
in acid sphingomyelinase (ASM), involves severe neurodegeneration and early death …

Key points Adeno‐associated viral vector was used to elevate the expression of muscle
specific kinase (MuSK) and rapsyn (a cytoplasmic MuSK effector protein) in the tibialis …

Background Skeletal muscle myopathy and exercise intolerance are diagnostic hallmarks of
heart failure (HF). However, the molecular adaptations of skeletal muscles during dilated …

Huntington's disease (HD) is a disorder characterized by chronic involuntary movements,
dementia, and psychiatric symptoms. It is caused by a mutation in the gene that encodes for …