Plasmodium Genomics and Genetics: New Insights into Malaria Pathogenesis, Drug Resistance, Epidemiology, and Evolution
Protozoan Plasmodium parasites are the causative agents of malaria, a deadly disease that
continues to afflict hundreds of millions of people every year. Infections with malaria …
continues to afflict hundreds of millions of people every year. Infections with malaria …
[HTML][HTML] Sticking for a cause: the falciparum malaria parasites cytoadherence paradigm
After a successful invasion, malaria parasite Plasmodium falciparum extensively remodels
the infected erythrocyte cellular architecture, conferring cytoadhesive properties to the …
the infected erythrocyte cellular architecture, conferring cytoadhesive properties to the …
Antibodies against Plasmodium falciparum malaria at the molecular level
JP Julien, H Wardemann - Nature Reviews Immunology, 2019 - nature.com
Malaria is a vector-borne disease of global importance, with the vast majority of its life-
threatening cases caused by infection with Plasmodium falciparum parasites. Repeated …
threatening cases caused by infection with Plasmodium falciparum parasites. Repeated …
Fenozyme protects the integrity of the blood–brain barrier against experimental cerebral malaria
Cerebral malaria is a lethal complication of malaria infection characterized by central
nervous system dysfunction and is often not effectively treated by antimalarial combination …
nervous system dysfunction and is often not effectively treated by antimalarial combination …
[HTML][HTML] Erythrocyte glycophorins as receptors for Plasmodium merozoites
E Jaskiewicz, M Jodłowska, R Kaczmarek, A Zerka - Parasites & vectors, 2019 - Springer
Glycophorins are heavily glycosylated sialoglycoproteins of human and animal erythrocytes.
In humans, there are four glycophorins: A, B, C and D. Glycophorins play an important role in …
In humans, there are four glycophorins: A, B, C and D. Glycophorins play an important role in …
Effect of the ABO blood group on susceptibility to severe malaria: a systematic review and meta-analysis
Understanding how ABO blood group interacts with Plasmodium falciparum (P. falciparum)
infection may facilitate development of antimalarial treatments and vaccines. This study …
infection may facilitate development of antimalarial treatments and vaccines. This study …
Severe malaria: update on pathophysiology and treatment
JA Brejt, LM Golightly - Current Opinion in Infectious Diseases, 2019 - journals.lww.com
Despite advances in our understanding of malarial pathogenesis much remains unknown.
Antimalarial agents eradicate parasites but no treatments are available to prevent or …
Antimalarial agents eradicate parasites but no treatments are available to prevent or …
Malaria molecular epidemiology: an evolutionary genetics perspective
AA Escalante, MA Pacheco - Microbiology spectrum, 2019 - Am Soc Microbiol
Malaria is a vector-borne disease that involves multiple parasite species in a variety of
ecological settings. However, the parasite species causing the disease, the prevalence of …
ecological settings. However, the parasite species causing the disease, the prevalence of …
Transmission-blocking vaccines: old friends and new prospects
FK Acquah, J Adjah, KC Williamson… - Infection and …, 2019 - Am Soc Microbiol
In the progression of the life cycle of Plasmodium falciparum, a small proportion of asexual
parasites differentiate into male or female sexual forms called gametocytes. Just like their …
parasites differentiate into male or female sexual forms called gametocytes. Just like their …
Dissecting the gene expression, localization, membrane topology, and function of the Plasmodium falciparum STEVOR protein family
During its intraerythrocytic development, the malaria parasite Plasmodium falciparum
exposes variant surface antigens (VSAs) on infected erythrocytes to establish and maintain …
exposes variant surface antigens (VSAs) on infected erythrocytes to establish and maintain …